XY1
- CAS NO.：1624117-53-8
- Empirical Formula: C17H19N3O2
- Molecular Weight: 297.35
- MDL number: MFCD28397755
- Update Date: 2026-07-17 09:03:53
What is XY1?
Description
Protein arginine N-methyltransferase 3 (PRMT3, ) is a predominantly cytoplasmic enzyme that is constitutively expressed. SGC707 is a potent, selective allosteric inhibitor of PRMT3 (IC50 = 50 nM). It inhibits the methylation of histones in cells with an IC50 value below 1 μM. XY1 is a close analog of SGC707 that is completely inactive against PRMT3 at concentrations as high as 100 μM. It is intended to be used as a negative control for SGC707 in studies involving PRMT3 action. See the Structural Genomics Consortium (SGC) website for more information.
The Uses of XY1
XY1 acts as a close analog of SGC707 that is completely inactive against PRMT3, inhibiting the methylation of histones in cells.
Storage
Store at +4°C
Properties of XY1
| Boiling point: | 514.8±42.0 °C(Predicted) |
| Density | 1.284±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | DMF: 10 mg/ml; DMSO: 25 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml |
| form | A crystalline solid |
| pka | 12.62±0.46(Predicted) |
| color | White to off-white |
Safety information for XY1
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for XY1
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