XL147
- CAS NO.：956958-53-5
- Empirical Formula: C21H16N6O2S2
- Molecular Weight: 448.52
- MDL number: MFCD16621245
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-27 17:00:41
What is XL147?
Description
XL147 analog is an analog of XL147 .
The Uses of XL147
XL147 analogue is one of Pyrimidine derivatives as JAK-2 inhibitors in combination with other agents and their use in the treatment of diseases.
What are the applications of Application
XL-147 derivative 2 is an ATP-competetive class I PI3K inhibitor
Definition
ChEBI: XL147 is a sulfonamide that is the N-4-toluenesulfonyl (N-tosyl) derivative of N-(2,1,3-benzothiadiazol-5-yl)quinoxaline-2,3-diamine. A selective PI3K inhibitor used in cancer treatment. It has a role as an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor and an antineoplastic agent. It is a sulfonamide, a quinoxaline derivative, a benzothiadiazole and an aromatic amine.
Properties of XL147
| Boiling point: | 638.9±65.0 °C(Predicted) |
| Density | 1.538 |
| storage temp. | Store at -20°C |
| solubility | ≥22.45 mg/mL in DMSO with gentle warming; insoluble in H2O; insoluble in EtOH |
| form | solid |
| pka | 6.71±0.30(Predicted) |
| color | Light brown to brown |
Safety information for XL147
Computed Descriptors for XL147
New Products
5-bromo-4-fluoro-2-nitrobenzaldehyde (R)-(-)-2-Amino-1-propanol Cyclobutanone Fmoc-OSu 1-(2-Chloroethyl)pyrrolidine Hydrochloride 2-Amino-2-(4-methylphenyl)acetic acid Obidoxime hydrochloride API Decanoic acid, 2-[4-(phenylmethoxy)phenyl]ethyl ester Piperazine, 1-(3-methoxyphenyl)-, hydrochloride (1:1) 4-Bromo-2,6-difluoroaniline 4 pentyn 1 ol N-Vinylformamide Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 2-Pentyn-1-oL 4-Nitrobenzotrifluoride N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine Pirtobrutinib intd. 2-Butyn-1-oLRelated products of tetrahydrofuran
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