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HomeProduct name listWAY-202196

WAY-202196

WAY-202196 Structural

What is WAY-202196?

Biological Activity

WAY-202196 is a nonsteroidal selective estrogen receptor-beta (ERβ) agonist.

in vivo

WAY-202196 is a nonsteroidal selective estrogen receptor-β (ERβ) agonist. It significantly reduces histopathologic evidence of injury to the gastrointestinal mucosal surface (0.7±0.1 vs. 2.3±0.2 for control; p< 0.05). The mucosal mass of 10-cm segments of small bowel mucosa shows better preservation of mucosal mass than control treatment (63±20 [ERB-196] vs. 31±24 [control]), but this difference fails to reach statistical significance (p<0.06).

Properties of WAY-202196

Boiling point: 497.0±45.0 °C(Predicted)
Density  1.45±0.1 g/cm3(Predicted)
pka 8.10±0.20(Predicted)
form  Solid
color  Light brown to brown

Safety information for WAY-202196

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for WAY-202196

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