VZRIHFZJVIOJBE-UHFFFAOYSA-N
- CAS NO.：1240494-13-6
- Empirical Formula: C19H16BFN2O3S
- Molecular Weight: 382.22
- MDL number: MFCD28963933
- Update Date: 2026-07-17 09:03:53
What is VZRIHFZJVIOJBE-UHFFFAOYSA-N?
Description
SX-517 is a potent noncompetitive boronic acid CXCR1/2 antagonist. SX-517 inhibited CXCL1-induced Ca(2+) flux (IC50 = 38 nM) in human PMNs but had no effect on the Ca(2+) flux induced by C5a, fMLF, or PAF. SX-517 is the first reported boronic acid chemokine antagonist and represents a novel pharmacophore for CXCR1/2 antagonism.
Properties of VZRIHFZJVIOJBE-UHFFFAOYSA-N
| Density | 1.39±0.1 g/cm3(Predicted) |
| pka | 8.45±0.53(Predicted) |
| form | Solid |
| color | White to off-white |
Safety information for VZRIHFZJVIOJBE-UHFFFAOYSA-N
Computed Descriptors for VZRIHFZJVIOJBE-UHFFFAOYSA-N
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