VX-222
- CAS NO.:1026785-59-0
- Empirical Formula: C25H35NO4S
- Molecular Weight: 445.61
- MDL number: MFCD18089858
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-08-20 16:56:16
What is VX-222?
Description
Lomibuvir is a non-nucleoside inhibitor of the RNA-directed RNA polymerase of hepatitis C virus (HCV; Ki = 17 nM) that inhibits primer-dependent RNA synthesis selectively over de novo RNA synthesis. It inhibits HCV replication in Huh7.5 cells expressing the 1b/Con1 HCV subgenomic replicon (EC50 = 5 nM).
The Uses of VX-222
VX-222, s a novel, potent and selective inhibitor of HCV polymerase .
Definition
ChEBI: 5-(3,3-dimethylbut-1-ynyl)-3-[(4-hydroxycyclohexyl)-[(4-methylcyclohexyl)-oxomethyl]amino]-2-thiophenecarboxylic acid is a thiophenecarboxylic acid.
Properties of VX-222
| Boiling point: | 640.5±55.0 °C(Predicted) |
| Density | 1.21 |
| storage temp. | Store at -20°C |
| solubility | ≥44.6 mg/mL in DMSO; insoluble in H2O; ≥97.2 mg/mL in EtOH |
| form | solid |
| pka | 3.67±0.10(Predicted) |
Safety information for VX-222
| Signal word | Warning |
| Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for VX-222
New Products
3-azanyl-3-phenyl-propanoic acid 3-AMINO-3-(2-METHYLPHENYL)PROPANOIC ACID 3-AMINO-3-M-TOLYL-PROPIONIC ACID Nitroso Irbesartan N-Nitroso Nortriptyline 1-nitro-3,5-dimethyl adamantine (NMEM) 3-(2-aminoethyl) benzene sulfonamide Nabumetone Impurity 5 2,2-dibromo-1-cyclopropyl-2-(2-fluorophenyl)ethan-1-one 4-dimethylaminopyridine 3-Bromo-2-Methyl-5-Nitropyridine 2-Chloro Isonicotinic acid methyl ester 2-(Ethoxymethylene)propanedinitrile 5-Bromo-3-Methyl-2-Pyridinecarboxylic acid 5-Chloro-pyridine-2-carboxylic acid amideRelated products of tetrahydrofuran







![1H-Pyrrole-2-carboxaMide, 4-[2-[(2-chloro-4-fluorophenyl)aMino]-5-Methyl-4-pyriMidinyl]-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-](https://img.chemicalbook.in/CAS/GIF/896720-20-0.gif)
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