VAR10300 dihydrochloride

Synonym(s):5-[N-methyl-N-propargylaminomethyl]-8-hydroxyquinoline dihydrochloride;M-30 dihydrochloride;VAR10300 dihydrochloride

CAS NO.：64821-19-8
Empirical Formula: C14H15ClN2O
Molecular Weight: 262.74
MDL number: MFCD20488063
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-11 15:21:01

What is VAR10300 dihydrochloride?

The Uses of VAR10300 dihydrochloride

M 30 Dihydrochloride is a potent and brain selective monoamine oxidase (MAO) inhibitor (EC50 values are 37 and 57 nM for MAO-A and MAO-B, respectively). Also an iron chelator with antioxidant properties. Protects cells against 6-OHDA (Cat. No. 2547) induced apoptosis. Attenuates MPTP depletion of DA and increases striatal monoamine levels in a mouse Parkinson''s disease model.

Storage

Store at -20°C

Properties of VAR10300 dihydrochloride

storage temp.	2-8°C
solubility	DMSO, heptane and xylene: ≥21mg/mL
form	powder
color	green-yellow
Water Solubility	Soluble to 100 mM in water

Safety information for VAR10300 dihydrochloride

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H318:Serious eye damage/eye irritation
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection.

Computed Descriptors for VAR10300 dihydrochloride

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