URAT1 inhibitor 1
- CAS NO.：2268720-62-1
- Empirical Formula: C19H15Br2N5O2S2
- Molecular Weight: 569.29
- MDL number: MFCD32067902
- Update Date: 2026-07-27 17:00:41
What is URAT1 inhibitor 1?
Biological Activity
URAT1 inhibitor 1 (1g) is a uric acid transporter 1 (URAT1) inhibitor, with an IC50 of 32 nM. URAT1 inhibitor 1 has potential to treat hyperuricemia associated with gout[1].
References
[1]. Wu JW, et al. Synthesis, biological evaluation and 3D-QSAR studies of 1,2,4-triazole-5-substituted carboxylic acid bioisosteres as uric acid transporter 1 (URAT1) inhibitors for the treatment of hyperuricemia associated with gout. Bioorg Med Chem Lett. 2019 Feb 1;29(3):383-388.
Properties of URAT1 inhibitor 1
| storage temp. | Store at -20°C |
| solubility | DMSO : 125 mg/mL (219.57 mM; ultrasonic and warming and heat to 60°C) |
| form | Solid |
| color | Off-white to light yellow |
Safety information for URAT1 inhibitor 1
Computed Descriptors for URAT1 inhibitor 1
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