UR-144 Degradant

CAS NO.：1609273-88-2
Empirical Formula: C21H29NO
Molecular Weight: 311.46
Update Date: 2025-08-20 16:56:12

What is UR-144 Degradant?

Description

UR-144 is a synthetic cannabinoid (CB) analog of JWH 018 in which the naphthalene ring is substituted with a tetramethylcyclopropyl group. This substitution results in a compound which is a potent agonist for the peripheral CB₂ receptor. UR-144 Degradant is a common impurity observed during GC-MS analysis of samples containing UR-144. The opened ring of the degradant is presumed to be produced during heating of UR-144. This structure gives rise to a prominent fragment ion that is 15 amu greater than the base peak of UR-144. This pattern is consistent with McLafferty rearrangement of the degradant which does not occur with the parent compound.

The Uses of UR-144 Degradant

3,??3,??4-??Trimethyl-??1-??(1-??pentyl-??1H-??indol-??3-??yl)??-4-??penten-??1-??one is a potent agonist for the peripheral CB2 receptor and a synthetic cannabinoid. It can be used to develop analytical assays that detects UR-??144 and its metabolites.

Properties of UR-144 Degradant

Boiling point:	447.3±28.0 °C(Predicted)
Density	0.96±0.1 g/cm3(Predicted)
solubility	DMF: 5 mg/ml; DMSO: 5 mg/ml; Ethanol: 12.5 mg/ml; Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml

Safety information for UR-144 Degradant

Computed Descriptors for UR-144 Degradant

New Products

2-Ethoxyphenol Methyl 2-methoxy-5-sulfamoylbenzoate 3,6-Dichloropyridazine Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate 3,6-Dichloro-4-Isopropylpyridazine 2-[(2-Ethoxyphenoxy)methyl]oxirane 4-Morpholinoaniline 2-Chloromethyl-6-methyl-pyridine 1-Indanone tert-Butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate 2-Pyridinecarboxaldehdye 6-Methyl-2-pyridinemethanol 4-Bromo-2-fluoro-N-methylbenzamide 3-Azetidinecarboxylic acid N-(2-(4-((4-Fluorobenzyl)carbamoyl)-5-hydroxy-6-methoxypyrimidin-2-yl)propan-2-yl)-5-methyl-1,3,4-oxadiazole-2-carboxamide (R)-4-Boc-morpholine-3-carboxylic acid (Required high chiral purity NLT:99.5%) Tetrahydro-3-(2-methyl-2- nitropropyl)-2H-pyran-2-one 3-Bromo-2-fluorobenzonitrile Desoximetasone Boron Triiodide Nicotinic acid RAPAMYCIN Pentachlorobenzonitrile Budesonide