Unc51.1
Synonym(s):ATG1;FLJ38455;UNC51;Unc51.1
- Molecular Weight: 0
- Update Date: 2026-01-13 11:21:15
What is Unc51.1?
The Uses of Unc51.1
GST-ULK1 has been used in in vitro kinase assay.
General Description
Unc-51 like autophagy activating kinase 1 (ULK1) is a serine/threonine protein kinase which forms a component of the ULK1 protein kinase complex. This protein complex also contains the adaptor proteins ATG (autophagy-related) 13, RB1CC1/FIP200 (RB1-inducible coiled-coil 1), and ATG101. The gene encoding this protein is localized on human chromosome 12q24.33.
Biochem/physiol Actions
Unc-51 like autophagy activating kinase 1 (ULK1) protein kinase plays a crucial role in the control of autophagy initiation. This protein is responsible for activating a cascade of signaling pathways which results in the formation of phagosomes. ULK1 is also required for the control of the expression of key interferon-stimulated genes (ISGs).
Properties of Unc51.1
| storage temp. | -20°C |
| form | buffered aqueous glycerol solution |
Safety information for Unc51.1
Computed Descriptors for Unc51.1
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