Unc-45 homolog B (C. elegans)

Synonym(s):Anti-CMYA4;Anti-FLJ38610;Anti-MGC119540;Anti-MGC119541;Unc-45 homolog B (C. elegans)

Molecular Weight: 0
Update Date: 2023-04-23 13:52:06

What is Unc-45 homolog B (C. elegans)?

General Description

UNC45B (unc-45 myosin chaperone B)?codes for a myosin-specific chaperone. It is expressed in the heart and skeletal muscle tissue. It belongs to the UCS (UNC-45/CRO1/She4p) family of proteins. UNC-45 protein consists of an N-terminal tetratricopeptide repeat (TPR) domain along with the canonical UCS domain. It is located on human chromosome 17q12.

Biochem/physiol Actions

UNC45B (unc-45 myosin chaperone B) helps in the assembly of type II myosins. It plays an important role in myoblast fusion and sarcomere organization. UNC45B plays a vital role in the progression of cardiomyopathy and in the breast cancer tumor growth.

Properties of Unc-45 homolog B (C. elegans)

storage temp.	-20°C
form	buffered aqueous solution

Safety information for Unc-45 homolog B (C. elegans)

Computed Descriptors for Unc-45 homolog B (C. elegans)

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