Ufiprazole
Synonym(s):5-Methoxy-2-{[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]thio}-1H-benzimidazole;6-Methoxy-2-{[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]thio}-1H-benzimidazole;Omeprazole impurity C (PhEur);Pyrmetazol;Ufiprazole
- CAS NO.：73590-85-9
- Empirical Formula: C17H19N3O2S
- Molecular Weight: 329.42
- MDL number: MFCD00869021
- EINECS: 615-997-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-12-04 16:42:01
What is Ufiprazole?
Description
Omeprazole sulfide is an intermediate used in the production of the gastric proton pump inhibitors, omeprazole and esomeprazole . As a degradation product, it is reported to be a direct-acting inhibitor of cytochrome P450 2C19 in pooled human liver microsomes (IC50 = 9.7 μM).
The Uses of Ufiprazole
Ufiprazole (Omeprazole sulfide) is a metabolite of Omeprazole, a proton pump inhibitor. Omeprazole sulfide is a direct-acting inhibitor of CYP2C19 in pooled human liver microsomes. In addition, Ufiprazole is also a weak BRS-3 agonist.
The Uses of Ufiprazole
Omeprazole Sulfide (Esomeprazol EP Impurity C(Omeprazole EP Impurity C)) is a metabolite of Omeprazole.
What are the applications of Application
Omeprazole Sulfide is an Omeprazole metabolite
Definition
ChEBI: Omeprazole sulfide is a member of benzimidazoles.
Biological Activity
Ufiprazole (Omeprazole sulfide) is an intermediate in the production of gastric proton pump inhibitors omeprazole and esomeprazole.
Properties of Ufiprazole
| Melting point: | 122.0 to 126.0 °C |
| Boiling point: | 539.7±60.0 °C(Predicted) |
| Density | 1.28±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 9.81±0.10(Predicted) |
| color | White to Off-White |
| λmax | 307nm(MeOH)(lit.) |
| InChI | InChI=1S/C17H19N3O2S/c1-10-8-18-15(11(2)16(10)22-4)9-23-17-19-13-6-5-12(21-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20) |
| CAS DataBase Reference | 73590-85-9(CAS DataBase Reference) |
Safety information for Ufiprazole
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Ufiprazole
| InChIKey | XURCIPRUUASYLR-UHFFFAOYSA-N |
| SMILES | C1(SCC2=NC=C(C)C(OC)=C2C)NC2=CC(OC)=CC=C2N=1 |
Ufiprazole manufacturer
Clickchem Research LLP
2Y
Phone:+91-8140031133
Whatsapp: +91- 8140031133
product: 73590-85-9 OMEPRAZOLE EP IMPURITY C 90 % Above
SRINI PHARMACEUTICALS PVT LTD
1Y
Phone:+91-7093200121
Whatsapp: +91-7093200121
product: 5-methoxy-2-[[(4-methoxy-3, 5-dimethyl-2-pyridinyl) methyl]thio]-1H- benzimidazole. 73590-85-9 98%
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