TYRPHOSTIN AG 835
- CAS NO.：133550-37-5
- Empirical Formula: C18H16N2O3
- Molecular Weight: 308.33
- MDL number: MFCD00209855
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-06 15:52:27
What is TYRPHOSTIN AG 835?
The Uses of TYRPHOSTIN AG 835
Tyrphostin B44, (+) enantiomer is an EGFR kinase inhibitor.
What are the applications of Application
Tyrphostin B44, (+) enantiomer is an EGFR kinase inhibitor
Biological Activity
Epidermal growth factor receptor (EGFR) kinase inhibitor (IC 50 = 0.86 μ M). Slightly less active than the (-) enantiomer ((R)-(E)-2-Cyano-3-(3',4'-dihydroxyphenyl)-N-(1-phenylethyl)-2-propenamide ).
Properties of TYRPHOSTIN AG 835
| Melting point: | 146 °C |
| Boiling point: | 603.0±55.0 °C(Predicted) |
| Density | 1.299±0.06 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | DMSO or ethanol: soluble |
| form | powder to crystal |
| pka | 8.81±0.10(Predicted) |
| color | Light yellow to Amber to Dark green |
Safety information for TYRPHOSTIN AG 835
| Signal word | Warning |
| Pictogram(s) |
 Health Hazard GHS08 |
| GHS Hazard Statements |
H371:Specific target organ toxicity, single exposure H373:Specific target organ toxicity, repeated exposure |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P405:Store locked up. P501:Dispose of contents/container to..… |
Computed Descriptors for TYRPHOSTIN AG 835
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