Tubastatin-A
- CAS NO.:1252003-15-8
- Empirical Formula: C20H21N3O2
- Molecular Weight: 335.4
- MDL number: MFCD18071463
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-07-04 15:30:27
What is Tubastatin-A?
Definition
ChEBI: A pyridoindole that is 1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indole which is substituted on the tetrahydropyridine nitrogen by a methyl group and on the indole nitrogen by a p-[N-(hydroxy)aminoca bonyl]benzyl group. It is a histone deacetylase 6 (HDAC6) inhibitor that is selective against all the other isozymes (1000-fold) except HDAC8 (57-fold).
Properties of Tubastatin-A
| Density | 1.28±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | insoluble in EtOH; insoluble in H2O; ≥10.75 mg/mL in DMSO |
| form | solid |
| pka | 8.95±0.10(Predicted) |
| color | Off-white to light yellow |
Safety information for Tubastatin-A
Computed Descriptors for Tubastatin-A
New Products
(E)-1-Ethoxyethene-2-boronic Acid Pinacol Ester 1,3-Diethyl-1,3-Diphenylurea 3-(4-morpholinophenylamino)-5-amino-1H-pyrazole-4-carbonitrile Methyl 2-methylquinoline-6-carboxylate 2,4-dihydroxybenzaldehyde 2-((4-morpholinophenylamino) (methylthio) methylene) malononitrile 1,3-Di Iodo Benzene Methyl 2-oxo-2,3-dihydrobenzo[d]oxazole-7-carboxylate 4-(2-Aminoethyl)-7-hydroxy-2H-chromoen-2-one 3-Hydroxy-4-nitrobromobenzene 2-Ethyl-1,4-diaminobenzene 2-Ethylhexyl 4-aminobenzoate Thio AcetamideRelated products of tetrahydrofuran
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