Trimethyl lock succinimidyl ester

Synonym(s):3-(2-Acetoxy-4,6-dimethylphenyl)-3-methylbutyric acid N-hydroxysuccinimide ester;Trimethyl lock NHS;Trimethyl lock succinimidyl ester

Molecular Weight: 0
MDL number: MFCD24386387
Update Date: 2025-01-27 09:38:02

What is Trimethyl lock succinimidyl ester?

The Uses of Trimethyl lock succinimidyl ester

This ′trimethyl lock′ derivative is activated with a succinimidyl ester for modification of amine containing compounds and biomolecules. After modification of your amine of interest, your now ′masked′ molecule can be released by cleavage of the ester, which can be achieved by cellular esterases. This triggers a rapid lactonization reaction of the ′trimethyl lock′ to regenerate your original amine-containing molecule. This approach has been applied to release of fluorophores, peptides, nucleic acids as well as small molecule drugs.

Properties of Trimethyl lock succinimidyl ester

Melting point:	107-112 °C
storage temp.	2-8°C

Safety information for Trimethyl lock succinimidyl ester

Computed Descriptors for Trimethyl lock succinimidyl ester

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