TRIFLUOROACETALDEHYDE ETHYL HEMIACETAL
Synonym(s):1-Ethoxy-2,2,2-trifluoroethanol
- CAS NO.：433-27-2
- Empirical Formula: C4H7F3O2
- Molecular Weight: 144.09
- MDL number: MFCD00000441
- EINECS: 207-087-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:27:07
What is TRIFLUOROACETALDEHYDE ETHYL HEMIACETAL?
Chemical properties
clear colorless liquid
The Uses of TRIFLUOROACETALDEHYDE ETHYL HEMIACETAL
Trifluoroacetaldehyde Ethyl Hemiacetal is used in the synthesis of peptidomimetic inhibitors of the human cytomegalovirus protease. It is also used in the synthesis of transforming growth factor-β typ e receptor inhibitors.
The Uses of TRIFLUOROACETALDEHYDE ETHYL HEMIACETAL
Alternative to gaseous unstable trifluoroacetaldehyde: used to prepare α-trifluoromethylated alcohols for antifungals, antitumor, and chemotherapeutic agents.1,2,3
The Uses of TRIFLUOROACETALDEHYDE ETHYL HEMIACETAL
Trifluoroacetaldehyde Ethyl Hemiacetal is used in the synthesis of peptidomimetic inhibitors of the human cytomegalovirus protease. It is also used in the synthesis of transforming growth factor-β type receptor inhibitors.
Properties of TRIFLUOROACETALDEHYDE ETHYL HEMIACETAL
| Boiling point: | 104-105 °C/745 mmHg (lit.) |
| Density | 1.221 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | 97 °F |
| storage temp. | 2-8°C |
| solubility | Chloroform, Ethyl Acetate |
| form | Liquid |
| pka | 10.57±0.20(Predicted) |
| Specific Gravity | 1.241 |
| color | Clear colorless |
| BRN | 906797 |
| CAS DataBase Reference | 433-27-2(CAS DataBase Reference) |
| NIST Chemistry Reference | Ethanol, 1-ethoxy-2,2,2-trifluoro-(433-27-2) |
| EPA Substance Registry System | Ethanol, 1-ethoxy-2,2,2-trifluoro- (433-27-2) |
Safety information for TRIFLUOROACETALDEHYDE ETHYL HEMIACETAL
| Signal word | Warning |
| Pictogram(s) |
 Flame Flammables GHS02  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H226:Flammable liquids H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for TRIFLUOROACETALDEHYDE ETHYL HEMIACETAL
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