trans-2-Hexenoic acid

CAS NO.：13419-69-7
Empirical Formula: C6H10O2
Molecular Weight: 114.14
MDL number: MFCD00002705
EINECS: 236-528-5
SAFETY DATA SHEET (SDS)
Update Date: 2025-09-25 17:15:13

What is trans-2-Hexenoic acid?

Description

trans-2-Hexenoic acid has a pleasant fatty characteristic and is long-lasting. This substance may be synthesized by condensation of butyraldehyde with malonic acid.

Chemical properties

white crystalline low melting solid

Chemical properties

trans-2-Hexenoic acid has a pleasant, fatty, characteristic, long-lasting odor.

Occurrence

Reported found in Japanese peppermint oil, apple, banana, bilberry, guava, pork fat, white wine, tea, starfruit, loquat and loganberry.

The Uses of trans-2-Hexenoic acid

(2E)-2-Hexenoic Acid is used in the synthesis of antitumor dehydroepiandrosteronederivatives. Also used in the synthesis of phosphatase 1B inhibitors.

What are the applications of Application

trans-2-Hexenoic acid is used in the synthesis of antitumor dehydroepiandrosteronederivatives

Definition

ChEBI: The (E)-stereoisomer of hexenoic acid.

Preparation

By condensation of butyraldehyde with malonic acid

Properties of trans-2-Hexenoic acid

Melting point:	33-35 °C (lit.)
Boiling point:	217 °C (lit.)
Density	0.965 g/mL at 25 °C (lit.)
vapor density	>1 (vs air)
refractive index	n20/D 1.438(lit.)
FEMA	3169 \| TRANS-2-HEXENOIC ACID
Flash point:	>230 °F
storage temp.	2-8°C
Water Solubility	Insoluble in water
solubility	Chloroform (Slightly), Methanol (Slightly)
form	powder to lump to clear liquid
pka	pK1:4.74 (25°C)
Specific Gravity	0.965
color	White or Colorless to Light yellow
Odor	at 1.00 % in propylene glycol. powerful fruity sweet warm herbal
JECFA Number	1361
BRN	1720443
CAS DataBase Reference	13419-69-7(CAS DataBase Reference)
NIST Chemistry Reference	2-Hexenoic acid, (E)-(13419-69-7)
EPA Substance Registry System	2-Hexenoic acid, (2E)- (13419-69-7)

Safety information for trans-2-Hexenoic acid

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05
GHS Hazard Statements	H314:Skin corrosion/irritation
Precautionary Statement Codes	P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.