Tigecycline Hydrochloride
- CAS NO.：197654-04-9
- Empirical Formula: C29H40ClN5O8
- Molecular Weight: 622.12
- MDL number: MFCD18071372
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-22 18:57:36
What is Tigecycline Hydrochloride?
Biological Activity
Tigecycline hydrochloride (GAR-936 hydrochloride) is a broad-spectrum glycylcycline antibiotic. The mean inhibitory concentration (MIC) of Tigecycline against E. coli (strain MG1655) is approximately 125 ng/mL. The MIC50 and MIC90 for Acinetobacter baumannii (A. baumannii) were 1 and 2 mg/L, respectively.
in vitro
Tigecycline (0.63-30 μM, preincubated for 4 days, treated for 72 h) inhibits AML2 cells and HL-60 cells with IC 50 s of 4.72±0.54 and 3.06±0.85 μM (freshly prepared).
in vivo
Tigecycline (50 mg/kg; intraperitoneal injection; twice a day; for 11 days) reduces tumor volume and weight in NOD/SCID mice.
Properties of Tigecycline Hydrochloride
| storage temp. | Store at -20°C |
| solubility | Soluble in DMSO |
| form | Powder |
Safety information for Tigecycline Hydrochloride
Computed Descriptors for Tigecycline Hydrochloride
Tigecycline Hydrochloride manufacturer
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