Thiophene-3-ethanol
Synonym(s):2-(3-Thienyl)ethanol;3-(2-Hydroxyethyl)thiophene
- CAS NO.：13781-67-4
- Empirical Formula: C6H8OS
- Molecular Weight: 128.19
- MDL number: MFCD00009766
- EINECS: 237-434-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 14:58:50
What is Thiophene-3-ethanol?
Chemical properties
Clear colorless to yellowish-brown liquid
The Uses of Thiophene-3-ethanol
3-Thiopheneethanol is used as a reagent in the synthesis of pH-responsive near-IR emitting conjugated polymer nanoparticles for cellular imaging and controlled-drug delivery. 3-Thiopheneethanol is also used as a reagent in the preparation of potent respiratory syncytial virus RNA polymerase inhibitors.
The Uses of Thiophene-3-ethanol
3-Thiopheneethanol [3-(2-hydroxyethyl)thiophene] was used in the synthesis of various ether and ester derivatives such as 3-(2-(benzyloxy)ethyl)thiophene, 3-[2-((triphenylmethyl)oxy)ethyl]thiophene, 3-[2-((trimethylsilyl)oxy)ethyl]thiophene, 3-[2-((dimethyl-tert-butylsilyl)oxy)ethyl]thiophene, 3-(2-acetoxyethyl)thiophene and 3-(2-(benzoyloxy)ethyl)thiophene.
Properties of Thiophene-3-ethanol
| Boiling point: | 110-111 °C14 mm Hg(lit.) |
| Density | 1.144 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | 199 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | Liquid |
| pka | 14.92±0.10(Predicted) |
| Specific Gravity | 1.144 |
| color | Clear colorless to yellow-brown |
| Water Solubility | Sparingly soluble in water(0.059 g/L at 25°C). |
| BRN | 107080 |
| CAS DataBase Reference | 13781-67-4(CAS DataBase Reference) |
| NIST Chemistry Reference | 3-Thiopheneethanol(13781-67-4) |
Safety information for Thiophene-3-ethanol
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H227:Flammable liquids |
| Precautionary Statement Codes |
P403+P235:Store in a well-ventilated place. Keep cool. |
Computed Descriptors for Thiophene-3-ethanol
| InChIKey | YYPNNBPPDFTQFX-UHFFFAOYSA-N |
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