Thiol-PEG6-t-butyl ester
- CAS NO.：1818294-40-4
- Empirical Formula: C19H38O8S
- Molecular Weight: 426.57
- MDL number: MFCD26127815
- Update Date: 2025-04-17 18:22:24
What is Thiol-PEG6-t-butyl ester?
Biological Activity
HS-PEG6-CH2CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Properties of Thiol-PEG6-t-butyl ester
| Boiling point: | 488.8±45.0 °C(Predicted) |
| Density | 1.072±0.06 g/cm3(Predicted) |
| pka | 9?+-.0.10(Predicted) |
Safety information for Thiol-PEG6-t-butyl ester
Computed Descriptors for Thiol-PEG6-t-butyl ester
New Products
2-(2-Chlorophenyl)glycine Propiolic Acid trans-3-Benzyloxy-4-methoxy-beta-nitrostyrene 1-(3-Hydroxy-4-methoxyphenyl)-2-nitroethene (±)-amino(2-fluorophenyl)acetic acid 1-Pentadecanol N-Vinylformamide 4 pentyn 1 ol Tween 80 or Polysorbate 80 4-(4-Αminophenyl)-3-Morpholinone 3-Morpholino-1-(4-(2-oxopiperidin-1-yl) phenyl)-5,6-dihyropyridin-2-(1H)-one 1-(4-Aminophenyl)-3-morpholino-5,6-dihydropyridin-2(1H)-one N-cyanoacetylurethane 1H-IndazoleRelated products of tetrahydrofuran
You may like
-
Thiol-peg6-t-butyl ester 95% CAS 1818294-40-4View Details
1818294-40-4 -
471-25-0 Propiolic Acid 98+View Details
471-25-0 -
84145-28-8 98+View Details
84145-28-8 -
trans-3-Benzyloxy-4-methoxy-beta-nitrostyrene 98+View Details
63909-29-5 -
2-(2-Chlorophenyl)glycine 88744-36-9 98+View Details
88744-36-9 -
40216-83-9 trans-4-Hydroxy-L-proline methyl ester hydrochloride 98+View Details
40216-83-9 -
629-76-5 98+View Details
629-76-5 -
1-(3-Hydroxy-4-methoxyphenyl)-2-nitroethene 98+View Details
39816-35-8
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.