TETRAMETHYL-1,3-CYCLOBUTANEDIONE
- CAS NO.:933-52-8
- Empirical Formula: C8H12O2
- Molecular Weight: 140.18
- MDL number: MFCD00001331
- EINECS: 213-269-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:12:10
What is TETRAMETHYL-1,3-CYCLOBUTANEDIONE?
Chemical properties
white crystalline powder
The Uses of TETRAMETHYL-1,3-CYCLOBUTANEDIONE
Tetramethyl-1,3-cyclobutanedione is used as a chemical for life science research. It is also used to make other chemical, as well as an chemical and organic intermediate.
Synthesis Reference(s)
Canadian Journal of Chemistry, 50, p. 3923, 1972 DOI: 10.1139/v72-619
Purification Methods
Crystallise the dione from *C6H6 and dry it in vacuo over P2O5 in an Abderhalden pistol. [Beilstein 7 III 3234, 7 IV 2004.]
Properties of TETRAMETHYL-1,3-CYCLOBUTANEDIONE
| Melting point: | 114-116 °C(lit.) |
| Boiling point: | 95-159 °C750 mm Hg(lit.) |
| Density | 1.0373 (rough estimate) |
| refractive index | 1.4580 (estimate) |
| Flash point: | 120-122°C/150mm |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | It is soluble in chloroform. |
| form | powder to crystal |
| color | White to Almost white |
| CAS DataBase Reference | 933-52-8(CAS DataBase Reference) |
| EPA Substance Registry System | 1,3-Cyclobutanedione, 2,2,4,4-tetramethyl- (933-52-8) |
Safety information for TETRAMETHYL-1,3-CYCLOBUTANEDIONE
Computed Descriptors for TETRAMETHYL-1,3-CYCLOBUTANEDIONE
| InChIKey | RGCDVHNITQEYPO-UHFFFAOYSA-N |
New Products
Cyclopropane-1,1-dicarboxylic acid Cefuroxime EP Impurity-A N-Nitroso hydroxy Cetrizine EP Impurity-A Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity Lantanoprost rc B Clidinium Bromide Impurity tert-Butyl (2S)-[1-amino-3-(4-iodophenyl)-1-oxopropan-2-yl]carbamate 4-amino-2-fluoro-N- methylbenzamide 5-Chloro-3- Methyl -1,3-2-benzoxazol-2(3H)-one N-(2-chloropyrimidin-4-yl)-N,2,3- trimethyl-2H- indazol 6-amine N-Boc-1,4-butanediamine 4-Bromo-2-fluoro-N-methylbenzamide valeronitrile 3-chlorobenzyl cyanide 3,4 Dimethoxy Benzylcyanide 3,4 Diethoxy Benzylcyanide 2-Chloro Benzylcyanide 3-Hydroxypropionitrile 5-azidovalericacid 6,6'-bis(difluoromethoxy)-2,2'-bis((3,4-dimethoxypyridin-2-yl)methylsulfinyl)-1H,1'H-5,5'-bibenzo[d]imidazole (1-((2'-(2-((1-((2'-(2H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methyl)-2H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methanol (1-((2'-(1-((1-((2'-(2H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methyl)-1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methanol (4-Methoxyphenyl) hydrazine HydrochlorideRelated products of tetrahydrofuran








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