Tetraisopropyl methylenediphosphonate

Chemical properties

Clear colorless to slightly yellow liquid

The Uses of Tetraisopropyl methylenediphosphonate

Tetraisopropyl Methylenediphosphonate is used in the preparation of E2-bisphosphonate conjugates as potential anti-osteoporosis agents. Also used in the preparation of AZT 5’-Triphosphate compounds which display inhibitory effects on HIV-1 reverse transcrpitase.

The Uses of Tetraisopropyl methylenediphosphonate

Tetraisopropyl methylenediphosphonate [T(iPr)MDP] forms a synergistic mixture with hydrogen dicarbollylcobaltate in nitrobenzene which was used in the extraction of europium and americium.
It may be used in the synthesis of the following:

• tetraisopropyl ethenylidenebisphosphonate.
• tetraisopropyl 4-acetylthiobutane-1,1-diphosphonate
• tetraisopropyl 2-(3,5-bis(bromomethyl)phenyl)ethane-1,1-diphosphonate

What are the applications of Application

Tetraisopropyl methylenediphosphonate is used in the preparation of AZT 5′-Triphosphate compounds

General Description

Tetraisopropyl methylenediphosphonate (IPCP) is a tetraisopropyl ester of methylenediphosphonic acid. It is an electroneutral ligand, reported to be synthesized from triisopropyl phosphate. Powder electron paramagnetic resonance (EPR) studies of tris complexes of Cu(II) complexes with IPCP has been analyzed.