Tetrahydroberberine
- CAS NO.：522-97-4
- Empirical Formula: C20H21NO4
- Molecular Weight: 339.39
- MDL number: MFCD00067284
- EINECS: 208-338-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-11-04 17:02:02
What is Tetrahydroberberine?
The Uses of Tetrahydroberberine
Tetrahydroberberine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Tetrahydroberberine is used for treatment of degenerative diseases or conditions associated with KATP channel signaling.
The Uses of Tetrahydroberberine
Canadine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Canadine is used for treatment of degenerative diseases or conditions associated with KATP channel signaling.
Definition
ChEBI: A berberine alkaloid that is 5,8,13,13a-tetrahydro-6H-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinoline substituted by methoxy groups at positions 9 and 10.
Properties of Tetrahydroberberine
| Melting point: | 166.5 °C |
| Boiling point: | 476.1±45.0 °C(Predicted) |
| Density | 1.33±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO: >10 mg/mL, soluble |
| form | solid |
| pka | 6.53±0.20(Predicted) |
| color | yellow |
Safety information for Tetrahydroberberine
Computed Descriptors for Tetrahydroberberine
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