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HomeProduct name listTetrahydroberberine

Tetrahydroberberine

  • CAS NO.:522-97-4
  • Empirical Formula: C20H21NO4
  • Molecular Weight: 339.39
  • MDL number: MFCD00067284
  • EINECS: 208-338-2
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2026-07-31 11:12:42
Tetrahydroberberine Structural

What is Tetrahydroberberine?

The Uses of Tetrahydroberberine

Tetrahydroberberine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Tetrahydroberberine is used for treatment of degenerative diseases or conditions associated with KATP channel signaling.

The Uses of Tetrahydroberberine

Canadine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Canadine is used for treatment of degenerative diseases or conditions associated with KATP channel signaling.

Definition

ChEBI: A berberine alkaloid that is 5,8,13,13a-tetrahydro-6H-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinoline substituted by methoxy groups at positions 9 and 10.

Properties of Tetrahydroberberine

Melting point: 166.5 °C
Boiling point: 476.1±45.0 °C(Predicted)
Density  1.33±0.1 g/cm3(Predicted)
storage temp.  Sealed in dry,Room Temperature
solubility  DMSO: >10 mg/mL, soluble
form  solid
pka 6.53±0.20(Predicted)
color  yellow

Safety information for Tetrahydroberberine

Computed Descriptors for Tetrahydroberberine

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