Terazosin hydrochloride dihydrate
Synonym(s):1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]piperazine hydrochloride dihydrate
- CAS NO.：70024-40-7
- Empirical Formula: C19H30ClN5O6
- Molecular Weight: 459.92
- MDL number: MFCD00941408
- EINECS: 629-697-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-03-13 23:13:44
What is Terazosin hydrochloride dihydrate ?
Chemical properties
White or slightly yellow, crystalline powder.
The Uses of Terazosin hydrochloride dihydrate
Terazosin Hydrochloride Dihydrate is an α-1-adrenergic blocker related to prazosin.
The Uses of Terazosin hydrochloride dihydrate
analgesic, antiinflammatory
What are the applications of Application
Terazosin Hydrochloride dihydrate is an α1-selective blocker
Manufacturing Process
To a solution of n-butanol (316 ml), water (24 ml) and N-(2- tetrahydrofuroyl)piperazine (20 g) were added, while stirring, 4-amino-2- chloro-6,7-dimethoxyquinazoline (22.2 g). The reaction mixture was heated to reflux and the reflux was maintained for about 9 h. Then the reaction mixture was cooled to room temperature and stirred at this temperature for about 10- 12 h. The crystals were collected by filtration, washed with n-BuOH and dried in vacuo at 40-50°C to yield 40.1 g (94%) of the 1-(4-amino-6,7-dimethoxy- 2-quinazolinyl)-4-(tetrahydrofuroyl)piperazine hydrochloride dihydrate
Therapeutic Function
Antihypertensive
Properties of Terazosin hydrochloride dihydrate
| Melting point: | 271-274°C |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Sparingly soluble in water, slightly soluble in methanol, very slightly soluble in ethanol (96 per cent), practically insoluble in acetone. |
| form | neat |
| form | Solid |
| color | White |
| CAS DataBase Reference | 70024-40-7(CAS DataBase Reference) |
Safety information for Terazosin hydrochloride dihydrate
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for Terazosin hydrochloride dihydrate
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Methanone](https://img.chemicalbook.in/CAS/GIF/105356-90-9.gif)
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