Tenovin-6
- CAS NO.：1011557-82-6
- Empirical Formula: C25H34N4O2S
- Molecular Weight: 454.63
- MDL number: MFCD11976906
- EINECS: 200-256-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 01:07:51
What is Tenovin-6?
The Uses of Tenovin-6
Tenovin-6 Hydrochloride, is a small molecule activator of p53 transcriptional activity. It acts as a potent SIRT1 and SIRT2 inhibitor as well.
What are the applications of Application
Tenovin-6 is an inhibitor of SIRT1, SIRT2, and SIRT3 and activator of p53
Definition
ChEBI: Tenovin-6 is a monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-(dimethylamino)pentanoic acid with the aromatic amino group of N-[(4-aminophenyl)carbamothioyl]-4-tert-butylbenzamide. It has a role as an antineoplastic agent, a Sir2 inhibitor and a p53 activator. It is a monocarboxylic acid amide, a member of thioureas and a tertiary amino compound.
Properties of Tenovin-6
| Density | 1.171±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20° C |
| solubility | ≥22.75 mg/mL in DMSO; insoluble in H2O; ≥2.62 mg/mL in EtOH with ultrasonic |
| form | solid |
| pka | 9.11±0.70(Predicted) |
| color | White to off-white |
Safety information for Tenovin-6
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Tenovin-6
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