Taurocholic acid
- CAS NO.：81-24-3
- Empirical Formula: C26H45NO7S
- Molecular Weight: 515.7
- MDL number: MFCD00053458
- EINECS: 201-336-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:50:13
What is Taurocholic acid?
Chemical properties
Crystals. Stable in air. Freely soluble in water; soluble in alcohol, almost insoluble in ether and ethyl acetate.
The Uses of Taurocholic acid
Taurocholic Acid is a choleretic steroid useful for the quantification of conjugated bile acids.
The Uses of Taurocholic acid
anti-inflammatory
Background
The product of conjugation of cholic acid with taurine. Its sodium salt is the chief ingredient of the bile of carnivorous animals. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is used as a cholagogue and cholerectic.
What are the applications of Application
Taurocholic Acid is a choleretic steroid useful for the quantification of conjugated bile acids
Definition
ChEBI: A bile acid taurine conjugate of cholic acid that usually occurs as the sodium salt of bile in mammals.
Metabolism
Not Available
Purification Methods
Crystallise the acid from EtOH/EtOAc/Et2O (amorphous m 125o) or EtOH/Et2O [Josephson Biochem J 29 1484 1935]. The sodium salt (hydrate) [312693-83-7, 345909-26-4 (xH2O)] crystallises from aqueous EtOH/Et2O with m 231-232o, [] D 23 +25.2o (c 1, H2O); and has max (H2SO4) at 303, 389 and 480nm. [Beilstein 10 III 2177, 10 IV 2078.]
Properties of Taurocholic acid
| Melting point: | 125°C (rough estimate) |
| alpha | D18 +38.8° (c = 2 in alcohol) |
| Density | 1.0902 (rough estimate) |
| refractive index | 1.5650 (estimate) |
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | Ethanol (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 1.4(at 25℃) |
| color | White to Off-White |
| Stability: | Hygroscopic |
| EPA Substance Registry System | Ethanesulfonic acid, 2-[[(3.alpha.,5.beta.,7.alpha.,12.alpha.)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino]- (81-24-3) |
Safety information for Taurocholic acid
Computed Descriptors for Taurocholic acid
New Products
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