TAUROCHOLIC ACID

CAS NO.：81-24-3
Empirical Formula: C26H45NO7S
Molecular Weight: 515.7
MDL number: MFCD00053458
EINECS: 201-336-2
SAFETY DATA SHEET (SDS)
Update Date: 2025-12-05 08:30:42

What is TAUROCHOLIC ACID?

Chemical properties

Crystals. Stable in air. Freely soluble in water; soluble in alcohol, almost insoluble in ether and ethyl acetate.

The Uses of TAUROCHOLIC ACID

Taurocholic Acid is a choleretic steroid useful for the quantification of conjugated bile acids.

The Uses of TAUROCHOLIC ACID

anti-inflammatory

Background

The product of conjugation of cholic acid with taurine. Its sodium salt is the chief ingredient of the bile of carnivorous animals. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is used as a cholagogue and cholerectic.

What are the applications of Application

Taurocholic Acid is a choleretic steroid useful for the quantification of conjugated bile acids

Definition

ChEBI: A bile acid taurine conjugate of cholic acid that usually occurs as the sodium salt of bile in mammals.

Metabolism

Not Available

Purification Methods

Crystallise the acid from EtOH/EtOAc/Et2O (amorphous m 125o) or EtOH/Et2O [Josephson Biochem J 29 1484 1935]. The sodium salt (hydrate) [312693-83-7, 345909-26-4 (xH2O)] crystallises from aqueous EtOH/Et2O with m 231-232o, [] D 23 +25.2o (c 1, H2O); and has max (H2SO4) at 303, 389 and 480nm. [Beilstein 10 III 2177, 10 IV 2078.]

Properties of TAUROCHOLIC ACID

Melting point:	125°C (rough estimate)
alpha	D18 +38.8° (c = 2 in alcohol)
Density	1.0902 (rough estimate)
refractive index	1.5650 (estimate)
storage temp.	Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility	Ethanol (Slightly), Methanol (Slightly)
form	Solid
pka	1.4(at 25℃)
color	White to Off-White
Stability:	Hygroscopic
EPA Substance Registry System	Ethanesulfonic acid, 2-[[(3.alpha.,5.beta.,7.alpha.,12.alpha.)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino]- (81-24-3)