TAUROCHOLIC ACID
- CAS NO.：81-24-3
- Empirical Formula: C26H45NO7S
- Molecular Weight: 515.7
- MDL number: MFCD00053458
- EINECS: 201-336-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-16 16:10:54
What is TAUROCHOLIC ACID?
Chemical properties
Crystals. Stable in air. Freely soluble in water; soluble in alcohol, almost insoluble in ether and ethyl acetate.
The Uses of TAUROCHOLIC ACID
Taurocholic Acid is a choleretic steroid useful for the quantification of conjugated bile acids.
The Uses of TAUROCHOLIC ACID
anti-inflammatory
Background
The product of conjugation of cholic acid with taurine. Its sodium salt is the chief ingredient of the bile of carnivorous animals. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is used as a cholagogue and cholerectic.
What are the applications of Application
Taurocholic Acid is a choleretic steroid useful for the quantification of conjugated bile acids
Definition
ChEBI: A bile acid taurine conjugate of cholic acid that usually occurs as the sodium salt of bile in mammals.
Metabolism
Not Available
Purification Methods
Crystallise the acid from EtOH/EtOAc/Et2O (amorphous m 125o) or EtOH/Et2O [Josephson Biochem J 29 1484 1935]. The sodium salt (hydrate) [312693-83-7, 345909-26-4 (xH2O)] crystallises from aqueous EtOH/Et2O with m 231-232o, [] D 23 +25.2o (c 1, H2O); and has max (H2SO4) at 303, 389 and 480nm. [Beilstein 10 III 2177, 10 IV 2078.]
Properties of TAUROCHOLIC ACID
| Melting point: | 125°C (rough estimate) |
| alpha | D18 +38.8° (c = 2 in alcohol) |
| Density | 1.0902 (rough estimate) |
| refractive index | 1.5650 (estimate) |
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | Ethanol (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 1.4(at 25℃) |
| color | White to Off-White |
| Stability: | Hygroscopic |
| EPA Substance Registry System | Ethanesulfonic acid, 2-[[(3.alpha.,5.beta.,7.alpha.,12.alpha.)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino]- (81-24-3) |
Safety information for TAUROCHOLIC ACID
Computed Descriptors for TAUROCHOLIC ACID
New Products
DL-beta-(3-Bromophenyl)alanine Tetrabutylammonium perchlorate N,O-Dimethylhydroxylamine hydrochloride (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid 2-Amino-5-bromo-4-(trifluoromethyl)pyridine（RM for Indian lab) N,N CARBONYL DIIMIDAZOLE Levothyroxine Impurity-F Montelukast EP Impurity-D/Montelukast USP Related Compound C Atorvastatin FXA Impurity/Atorvastatin Cyclic 6-Hydroxy Impurity Sodium Salt Isosulfan blue Keto N-Oxide Impurity Ivermectin Impurity F N-Nitroso des Methyl Tramadol/N-Nitroso-N-Desmethyl-Tramadol (R)-BoroLeu-(+)-Pinanediol-CF3COOH 1,4-bis(methylsulfonyl)butane 4-(5-amino-1-methyl-1h-benzoimidazol-2-yl)-butyric acid isopropyl ester. 5-Methyl-1,3-benzenediacetonitrile 4-Fluorothiophenol 1-methyl amino-2,4-dinitro benzene CSA (DL-10-Camphorsulfonic Acid) 2-Hydroxy-4-methylnicotinic acid 3-iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine (2S)-1-((2S,3S)-3-(2-methylbutyl)-4-oxooxetan-2-yl)pentadecan-2-yl formylleucinate 1-(3,5-dichlorophenyl)-2,2,2-trifluoroethane-1-sulfonyl chloride S-(1-(3,5-dichlorophenyl)-2,2,2-trifluoroethyl) ethanethioateRelated products of tetrahydrofuran
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