TAUROCHOLIC ACID
- CAS NO.：81-24-3
- Empirical Formula: C26H45NO7S
- Molecular Weight: 515.7
- MDL number: MFCD00053458
- EINECS: 201-336-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-03-13 23:13:44
What is TAUROCHOLIC ACID?
Chemical properties
Crystals. Stable in air. Freely soluble in water; soluble in alcohol, almost insoluble in ether and ethyl acetate.
The Uses of TAUROCHOLIC ACID
Taurocholic Acid is a choleretic steroid useful for the quantification of conjugated bile acids.
The Uses of TAUROCHOLIC ACID
anti-inflammatory
Background
The product of conjugation of cholic acid with taurine. Its sodium salt is the chief ingredient of the bile of carnivorous animals. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is used as a cholagogue and cholerectic.
What are the applications of Application
Taurocholic Acid is a choleretic steroid useful for the quantification of conjugated bile acids
Definition
ChEBI: A bile acid taurine conjugate of cholic acid that usually occurs as the sodium salt of bile in mammals.
Metabolism
Not Available
Purification Methods
Crystallise the acid from EtOH/EtOAc/Et2O (amorphous m 125o) or EtOH/Et2O [Josephson Biochem J 29 1484 1935]. The sodium salt (hydrate) [312693-83-7, 345909-26-4 (xH2O)] crystallises from aqueous EtOH/Et2O with m 231-232o, [] D 23 +25.2o (c 1, H2O); and has max (H2SO4) at 303, 389 and 480nm. [Beilstein 10 III 2177, 10 IV 2078.]
Properties of TAUROCHOLIC ACID
| Melting point: | 125°C (rough estimate) |
| alpha | D18 +38.8° (c = 2 in alcohol) |
| Density | 1.0902 (rough estimate) |
| refractive index | 1.5650 (estimate) |
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | Ethanol (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 1.4(at 25℃) |
| color | White to Off-White |
| Stability: | Hygroscopic |
| EPA Substance Registry System | Ethanesulfonic acid, 2-[[(3.alpha.,5.beta.,7.alpha.,12.alpha.)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino]- (81-24-3) |
Safety information for TAUROCHOLIC ACID
Computed Descriptors for TAUROCHOLIC ACID
New Products
Cyclopentane-1,2-dione 2,6-Dibromoaniline (4-Bromophenyl)(3-methoxyphenyl)methanone 4,5,7-Trimethyl-2(1H)-quinolinone 4-(6-HYDROXYHEXYLOXY)BENZOIC ACID 4-Hydroxy-6-methyl-1-(4-methylphenyl)-2naphthalenecarboxylic acid 2,6-Piperidinedione, 3-hydroxy-1-[(4-methoxyphenyl)methyl]- NA Cefuroxime EP Impurity-A N-Nitroso hydroxy Cetrizine EP Impurity-A Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity Lantanoprost rc B Clidinium Bromide Impurity 4 - fluoro- 2 - methoxy- 5 - nitroaniline 1-(2-amino-5-hydroxy phenyl)propan-1-one tert-butyl 4-(6-((7-cyclo pentyl -6-(dimethyl carbamoyl) -7H-pyrrolo [2,3-d]pyrimidin-2-yl) amino)pyridin-3-yl) piperazine-1-carboxylate (4-Fluoro-2-methoxy-5-nitro- phenyl)-[4- (1-methyl-1H- indol-3- yl)-pyrimidin-2-yl]- amine (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3- amine 5-bromo-2-chloro-N- cyclopentylpyrimidin-4- amine 2-Chloro Benzylcyanide 3,4 Diethoxy Benzylcyanide 3-chlorobenzyl cyanide 3,4 Dimethoxy BenzylcyanideRelated products of tetrahydrofuran
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