Sulindac sulfone
Synonym(s):(Z)-5-Fluoro-2-methyl-1-[p-(methylsulfonyl)benzylidene]indene-3-acetic acid
- CAS NO.：59973-80-7
- Empirical Formula: C20H17FO4S
- Molecular Weight: 372.41
- MDL number: MFCD01317811
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:52:10
What is Sulindac sulfone?
Chemical properties
Yellow Solid
The Uses of Sulindac sulfone
Sulindac Sulfone is an inhibitor of growth and inducer of apoptosis in cancer cell lines.
Definition
ChEBI: A sulfone metabolite of sulindac that inhibits cell growth by inducing apoptosis independently of cyclooxygenase inhibition. It inhibits the development and induces regression of premalignant adenomatous polyps. Lipoxygenase and Cox-2 inhibitor.
Properties of Sulindac sulfone
| Melting point: | 248-250°C |
| alpha | D -62° (c = 1 in CHCl3) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO: >25 mg/mL |
| form | solid |
| color | yellow |
| Stability: | Hygroscopic |
Safety information for Sulindac sulfone
Computed Descriptors for Sulindac sulfone
New Products
5-bromo-4-fluoro-2-nitrobenzaldehyde Cyclobutanone (R)-(-)-2-Amino-1-propanol Fmoc-OSu 1-(2-Chloroethyl)pyrrolidine Hydrochloride 2-Amino-2-(4-methylphenyl)acetic acid 2,4-Dihydroxybenzaldehyde Obidoxime hydrochloride API Pyrrolo[1,2-a]pyrimidine-6-carboxylic acid, 4,6,7,8-tetrahydro-4-oxo-, sodium salt (1:1), (6S) Dipropyl disulfide 4 pentyn 1 ol N-Vinylformamide Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 2-Butyn-1-oL 2-Pentyn-1-oL 4-Nitrobenzotrifluoride N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine Pirtobrutinib intd.Related products of tetrahydrofuran
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