Sulfosalicylic acid

CAS NO.：97-05-2
Empirical Formula: C7H6O6S
Molecular Weight: 218.18
MDL number: MFCD00007508
EINECS: 202-555-6
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-27 22:51:48

What is Sulfosalicylic acid ?

Chemical properties

Colorless crystals, colored pink by traces of iron. Very soluble in water.

The Uses of Sulfosalicylic acid

Sulfosalicylic Acid is a benzoic acid derivative with acetylcholinesterase inhibitory properties.

The Uses of Sulfosalicylic acid

Reagent for albumin, colorimetric reagent for ferric ion, intermediate for dyes, surfactants, catalysts, grease additives.

Definition

ChEBI: An arenesulfonic acid that is benzoic acid substituted by a hydroxy at position C-2 and a sulfo group at C-5.

Production Methods

Sulfosalicylic acid is obtained by heating one part of salicylic acid with 5 parts of concentrated sulfuric acid. It can also be prepared from the sulfochloride.

What are the applications of Application

2-Hydroxy-5-sulfobenzoic acid (Sulfosalicylic acid) forms a dihydrate and is used in analytical chemistry to detect albumins, iron, and mercury. Applications described in patents include the use as a heat stabilizer for polyacrylonitrile, as an additive used in the anodizing of metals, and – as a tributyltin compound – as an agent for the antibacterial protection of organic materials. The acid is also claimed to be suitable for a pregnancy test for horses.

Flammability and Explosibility

Not classified

Properties of Sulfosalicylic acid

Melting point:	120°C
Boiling point:	328.86°C (rough estimate)
Density	1.7563 (rough estimate)
vapor pressure	0.005Pa at 20℃
refractive index	1.5300 (estimate)
pka	-0.62±0.50(Predicted)
form	Liquid
color	Clear
Water Solubility	987g/L at 20℃
InChI	InChI=1S/C7H6O6S/c8-6-2-1-4(14(11,12)13)3-5(6)7(9)10/h1-3,8H,(H,9,10)(H,11,12,13)
CAS DataBase Reference	97-05-2(CAS DataBase Reference)
NIST Chemistry Reference	Benzoic acid, 2-hydroxy-5-sulfo-(97-05-2)
EPA Substance Registry System	Benzoic acid, 2-hydroxy-5-sulfo- (97-05-2)

Safety information for Sulfosalicylic acid

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05
GHS Hazard Statements	H314:Skin corrosion/irritation H318:Serious eye damage/eye irritation
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection. P310:Immediately call a POISON CENTER or doctor/physician. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.