SULFO-SMCC
Synonym(s):SMCC, Water-Soluble;Sulfo-SMCC;Sulfosuccinimidyl- trans-4-(N-maleimidomethyl)cyclohexane-1-carboxylate, Sulfo-SMCC;Sulfosuccinimidyl-trans-4-(N-maleimidomethyl)cyclohexane-1-carboxylate, Sulfo-SMCC
- CAS NO.：92921-24-9
- Empirical Formula: C16H19N2NaO9S
- Molecular Weight: 438.38
- MDL number: MFCD00054978
- EINECS: 618-887-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-29 20:57:39
What is SULFO-SMCC?
Description
Sulfo-SMCC is a commonly used hetero-bifunctional, noncleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively.
Chemical properties
Solid
The Uses of SULFO-SMCC
A sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. Spacer Arm: 11.6 Angstroms
The Uses of SULFO-SMCC
A sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. Spacer Arm: 11.6 Angstroms
What are the applications of Application
Sulfo-SMCC is a sulfhydryl- and amine-reactive crosslinker
Properties of SULFO-SMCC
| Melting point: | >270°C (dec.) |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| solubility | H2O: soluble2.5mg/mL |
| form | powder |
| color | white to light brown |
| Water Solubility | Soluble in water (2.5 mg/ml) and dimethyl formamide. |
| Stability: | Moisture Sensitive |
Safety information for SULFO-SMCC
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for SULFO-SMCC
| InChIKey | VUFNRPJNRFOTGK-UHFFFAOYSA-M |
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