Sulfamonomethoxine
Synonym(s):N1-(6-Methoxy-4-pyrimidinyl)sulfanilamide;4-Amino-N-(6-methoxy-4-pyrimidinyl)benzenesulfonamide;4-Methoxy-6-sulfanilamidopyrimidine;SMM
- CAS NO.：1220-83-3
- Empirical Formula: C11H12N4O3S
- Molecular Weight: 280.3
- MDL number: MFCD00063466
- EINECS: 624-483-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-22 22:14:22
What is Sulfamonomethoxine?
Chemical properties
White To Off-White Crystalline Powder
The Uses of Sulfamonomethoxine
Protein binding. Inhibitor of enzyme. Sulfamonomethoxine and Trimethoprim
The Uses of Sulfamonomethoxine
antibacterial
The Uses of Sulfamonomethoxine
Protein binding. Inhibitor of enzyme. Sulfamonomethoxine and Trimethoprim are used for treating porcine unknown hyperpyrexia.
What are the applications of Application
Sulfamonomethoxine is an enzyme inhibitor used to address hyperpyrexia
Definition
ChEBI: Sulfamonomethoxine is a sulfonamide and a member of benzenes.
Synthesis Reference(s)
The Journal of Organic Chemistry, 26, p. 2764, 1961 DOI: 10.1021/jo01066a034
General Description
Chemical structure: sulfonamide
Biochem/physiol Actions
Sulfamonomethoxine is a competitive inhibitor of dihydropteroate synthetase used to block the synthesis of folic acid.
Properties of Sulfamonomethoxine
| Melting point: | 203-2060C |
| Boiling point: | 513℃ |
| Density | 1.3936 (rough estimate) |
| refractive index | 1.6200 (estimate) |
| Flash point: | >110°(230°F) |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| solubility | methanol: soluble10mg/mL |
| form | powder |
| pka | pKa 5.94 (Uncertain) |
| color | white to white with yellow cast |
| Water Solubility | Soluble in water at 10mg/ml with warming. Also soluble in ethanol or methanol |
| BRN | 621128 |
| InChI | InChI=1S/C11H12N4O3S/c1-18-11-6-10(13-7-14-11)15-19(16,17)9-4-2-8(12)3-5-9/h2-7H,12H2,1H3,(H,13,14,15) |
| CAS DataBase Reference | 1220-83-3(CAS DataBase Reference) |
| EPA Substance Registry System | Sulfamonomethoxine (1220-83-3) |
Safety information for Sulfamonomethoxine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H317:Sensitisation, Skin H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Sulfamonomethoxine
| InChIKey | WMPXPUYPYQKQCX-UHFFFAOYSA-N |
| SMILES | C1(S(NC2C=C(OC)N=CN=2)(=O)=O)=CC=C(N)C=C1 |
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