Suberic acid

Synonym(s):Octanedioic acid;Suberic acid

CAS NO.：505-48-6
Empirical Formula: C8H14O4
Molecular Weight: 174.19
MDL number: MFCD00004428
EINECS: 208-010-9
SAFETY DATA SHEET (SDS)
Update Date: 2025-12-05 14:33:18

What is Suberic acid?

Description

It was firstly produced by nitric acid oxidation of cork (Latin suber) material and then from castor oil. The oxidation of ricinoleic acid produces, by splitting at the level of the double bond and at the level of the OH group, at the same time, suberic acid (octanedioic acid) and the next homologue azelaic acid. Suberic acid was used in the manufacture of alkyd resins and in the synthesis of polyamides leading to nylon.

Chemical properties

off-white crystalline powder

The Uses of Suberic acid

Suberic Acid is used in the preparation of reduction-sensitive micelles affecting their cellular uptake. This has potential application in delivery of anticancer drugs. It is also used in the fluoresc ent detection of amidinium-carboxylate and amidinium formation.

The Uses of Suberic acid

In the plastics industry.

Definition

ChEBI: An alpha,omega-dicarboxylic acid that is the 1,6-dicarboxy derivative of hexane.

Synthesis Reference(s)

Journal of the American Chemical Society, 81, p. 3677, 1959 DOI: 10.1021/ja01523a046

Purification Methods

Crystallise it from acetone. It sublimes at 300o without decomposition. [Beilstein 2 IV 2028.]

Properties of Suberic acid

Melting point:	140-144 °C(lit.)
Boiling point:	230 °C15 mm Hg(lit.)
Density	1.3010 (rough estimate)
vapor pressure	0Pa at 22.85℃
refractive index	1.4370 (estimate)
Flash point:	203 °C
storage temp.	Store below +30°C.
solubility	1.6g/l
form	Powder
pka	4.52(at 25℃)
color	White to cream
PH	3.79(1 mM solution);3.27(10 mM solution);2.76(100 mM solution);
Water Solubility	0.6 g/L (20 ºC)
Merck	14,8862
BRN	1210161
Stability:	Stable. Combustible. Incompatible with strong oxidizing agents, reducing agents, bases.
CAS DataBase Reference	505-48-6(CAS DataBase Reference)
NIST Chemistry Reference	Octanedioic acid(505-48-6)
EPA Substance Registry System	Octanedioic acid (505-48-6)

Safety information for Suberic acid

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.