STEAROYL-L-CARNITINE

Synonym(s):(2R)-3-Carboxy-N,N,N-trimethyl-2-[(1-oxooctadecyl)oxy]-1-propanaminium inner salt;L-Carnitine octadecanoyl ester;C18-Carnitine;Octadecanoyl-L-carnitine

CAS NO.：25597-09-5
Empirical Formula: C25H49NO4
Molecular Weight: 427.66086
MDL number: MFCD28902307
Update Date: 2026-01-21 16:49:52

What is STEAROYL-L-CARNITINE?

The Uses of STEAROYL-L-CARNITINE

Stearoyl-L-carnitine may be used as an analytical reference standard for the quantification of the analyte in biological fluids using chromatography-based techniques.

Definition

ChEBI: O-octadecanoyl-L-carnitine is an O-acyl-L-carnitine in which the acyl group is specified as stearoyl (octadecanoyl). It has a role as a human metabolite. It is functionally related to an octadecanoic acid.

General Description

Stearoyl-L-carnitine is a naturally occurring compound belonging to the acylcarnitine class of compounds as listed in the human metabolome database (HMBD). These compounds are reported to be used as biomarkers in the diagnosis of carnitine deficiency. It acts as a carrier of long chain acyl groups from activated fatty acids across the inner mitochondrial membrane into the mitochondrial matrix where they undergo β-oxidation to acetyl CoA to obtain usable energy via the citric acid cycle.

Biochem/physiol Actions

Stearoylcarnitine is found in significantly greater amounts in patients with carnitine palmitoyltransferase II deficiency. Carnitine palmitoyltransferase, in conjunction with acyl-CoA synthetase and carnitine/acylcarnitine translocase, provides the mechanism whereby long-chain fatty acids are transferred from the cytosol to the mitochondrial matrix to undergo beta-oxidation.

Properties of STEAROYL-L-CARNITINE

storage temp.	2-8°C
solubility	Water: 1 mg/mL (2.34 mM; ultrasonic and warming and heat to 80°C); DMSO: < 1 mg/mL (insoluble or slightly soluble)
form	Solid
color	White to off-white
optical activity	[α]/D -15±2°, c = 1 in methanol
BRN	7309670

Safety information for STEAROYL-L-CARNITINE

Computed Descriptors for STEAROYL-L-CARNITINE

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