STEAROYL ETHANOLAMIDE
Synonym(s):N-Stearoylethanolamine;NSE
- CAS NO.：111-57-9
- Empirical Formula: C20H41NO2
- Molecular Weight: 327.55
- MDL number: MFCD00045971
- EINECS: 203-883-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-03-10 21:10:33
What is STEAROYL ETHANOLAMIDE?
The Uses of STEAROYL ETHANOLAMIDE
Stearoyl Ethanolamide is a prolific fatty acid ethanolamide produced by PLD hydrolysis of membrane phospholipids. Stearoyl Ethanolamide is also used for studying the effect on endocannabinoid signalling and BBB integrity in systemic inflammation.
What are the applications of Application
Stearoyl Ethanolamide is a prolific fatty acid ethanolamide produced by PLD hydrolysis of membrane phospholipids
Definition
ChEBI: An N-(long-chain-acyl)ethanolamine that is the ethanolamide of octadecanoic acid.
Preparation
In the stirred state, fatty acids (1.0 mmol, 1.0 equiv) were added to CH2Cl2 (5 mL), followed by CDI (0.178 g, 1.1 mmol, 1.1 equiv). After 30 min, the amine (1.1 mmol, 1.1equiv.)was added. Added CH2Cl2 (25ml) and saturated NH4Cl aqueous solution after 12 h. HCl was added to the mixture to adjusted pH=2. After the organic phase was separated, the aqueous layer was further extracted with CH2Cl2 (3 × 10 mL). The organic phase was collected and placed on Na2SO4 to dried, and filtered. Finally, the product (STEAROYL ETHANOLAMIDE) was obtained by vacuum concentration.
Flammability and Explosibility
Non flammable
Properties of STEAROYL ETHANOLAMIDE
| Melting point: | 103-104 °C(Solv: ethanol (64-17-5)) |
| Boiling point: | 486.0±28.0 °C(Predicted) |
| Density | 0.904±0.06 g/cm3(Predicted) |
| vapor pressure | 0Pa at 20℃ |
| storage temp. | −20°C |
| solubility | DMF: >2 mg/ml; DMSO: >100 μg/ml; Ethanol: >2 mg/ml; PBS pH 7.2: >100 μg/ml |
| form | crystalline |
| pka | 14.49±0.10(Predicted) |
| color | White to light yellow |
| Water Solubility | 1mg/L at 20℃ |
| InChI | InChI=1S/C20H41NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)21-18-19-22/h22H,2-19H2,1H3,(H,21,23) |
| EPA Substance Registry System | N-(2-Hydroxyethyl)octadecanamide (111-57-9) |
Safety information for STEAROYL ETHANOLAMIDE
Computed Descriptors for STEAROYL ETHANOLAMIDE
| InChIKey | OTGQIQQTPXJQRG-UHFFFAOYSA-N |
| SMILES | C(NCCO)(=O)CCCCCCCCCCCCCCCCC |
New Products
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