STARBURST(R) (PAMAM) DENDRIMER, GENERATION 2.5

Synonym(s):Starburst PAMAM-G 3

CAS NO.：153891-46-4
Empirical Formula: [NH2(CH2)2NH2]:(G=4);dendriPAMAM(NHCH2CH2OH)64
Molecular Weight: 0
MDL number: MFCD00197936
SAFETY DATA SHEET (SDS)
Update Date: 2026-01-13 11:19:25

What is STARBURST(R) (PAMAM) DENDRIMER, GENERATION 2.5?

The Uses of STARBURST(R) (PAMAM) DENDRIMER, GENERATION 2.5

PAMAM-OH dendrimer can be used to formulate poorly water-soluble drugs to increase water solubility, and therefore enhance the bioavailability of these drugs. It can also be applied to catalysts and organic molecules, where dendrimers function as solubility enhancers and modifiers.

General Description

PAMAM-OH (poly(amidoamine) dendrimers are highly branched core-shell nanostructures with surface hydroxyl groups. The presence of hydroxyl groups on the surface of the PAMAM-OH dendrimer molecule leads to stronger interaction with the components of the cell membrane via the formation of hydrogen bonds. This type of interaction can modify the properties and function of cell membranes. PAMAM-OH dendrimers also have an advantage over PAMAM dendrimers in terms of cytotoxicity and aggregation problems because of the absence of amine functionality.

Properties of STARBURST(R) (PAMAM) DENDRIMER, GENERATION 2.5

Boiling point:	64.7 °C
Density	0.863 g/mL at 25 °C
refractive index	n20/D 1.367
Flash point:	52 °F
storage temp.	2-8°C
form	5 wt.% in methanol

Safety information for STARBURST(R) (PAMAM) DENDRIMER, GENERATION 2.5

Signal word	Danger
Pictogram(s)	Flame Flammables GHS02 Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08
GHS Hazard Statements	H225:Flammable liquids H370:Specific target organ toxicity, single exposure
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P280:Wear protective gloves/protective clothing/eye protection/face protection.

Computed Descriptors for STARBURST(R) (PAMAM) DENDRIMER, GENERATION 2.5

New Products

3-AMINO-3-(2-FLUORO-PHENYL)-PROPIONIC ACID Pentadecanoic acid Hendecanoic acid 2-AMINO-3-METHYLQUINOLINE HYDROCHLORIDE 3-Hydroxypropionitrile DL-3-Amino-3-(2-methoxyphenyl)propionic acid 5-Bromo-2-Fluoropyridine 2,3-Diamino-5-Chloropyridine 2-Amino-3-Hydroxypyridine 2,6-Diamino Pyridine 4-Amino-2-Chloropyridine 2-Hydroxy-4-Picoline 4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 4-Bromo-3-(ethoxymethyl)benzoic acid 2,4-Dichloro-5-methoxyaniline 4,6-Dichloro-2-(propylthio)pyrimidin-5-amine N2-Isobutyryl-2'-O-methylguanosine 2-chloro-5-methylpyridin-4-amine 4-Bromobenzaldehyde 2-Chloro-6-nitro benzothiazole 2-Amino-4-phenyl-thiazole 4-Chloro-2-methyl quinoline 2-(Chloromethyl) quinazolin-4(3H)-one 5-Phenyl-[1,3,4]-thiadiazol-2-amine