SR9011

CAS NO.：1379686-29-9
Empirical Formula: C23H31ClN4O3S
Molecular Weight: 479.04
MDL number: MFCD29472235
EINECS: 1379686-290-9
Update Date: 2026-07-18 07:23:31

What is SR9011?

The Uses of SR9011

SR 9011 is a synthetic REV-ERBα/β agonist with activity in vivo. It is a lead compound for a new class of cancer drugs associated with the body’s circadian clock.

What are the applications of Application

SR9011 has been used as a nuclear receptor subfamily 1 group D member 1 (NR1D1) receptor agonist:
to study its effects on microglial immune-metabolism
to study its effects on insulin secretion from human type 2 diabetes islet cells
to study its effects on thyroid-stimulating hormone β (TSHβ) gene expression

Properties of SR9011

Boiling point:	642.8±50.0 °C(Predicted)
Density	1.254±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Solid
pka	14.71±0.40(Predicted)
color	Dark Yellow to Very Dark Brown
InChI	InChI=1S/C23H31ClN4O3S/c1-2-3-4-12-25-23(29)27-13-11-19(16-27)15-26(14-18-5-7-20(24)8-6-18)17-21-9-10-22(32-21)28(30)31/h5-10,19H,2-4,11-17H2,1H3,(H,25,29)

Safety information for SR9011

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.