Contact us: +91 9550333722 040 - 40102781

Structured search

India

Choose your country
Different countries will display different contents

China United Kingdom South Korea Germany Japan India

Try our best to find the right business for you.

My chemicalbook

Welcome back!

Home Product name listSR3335

SR3335

Synonym(s):;N-(4-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)phenyl)thiophene-2-sulfonamide;N-[4-[2,2,2-Trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-2-thiophenesulfonamide;

CAS NO.：293753-05-6
Empirical Formula: C13H9F6NO3S2
Molecular Weight: 405.3358792
MDL number: MFCD02724814
SAFETY DATA SHEET (SDS)
Update Date: 2026-07-03 18:06:58

SR3335 Structural

What is SR3335?

Description

The retinoic acid receptor-related receptors (RORs) are orphan nuclear receptors with diverse putative roles. SR 3335 is a selective inverse agonist of RORα, competitively inhibiting the binding of 25-hydroxycholesterol to the ligand binding domain (K_i = 220 nM) and inhibiting constitutive transactivation activity (IC₅₀ = 480 nM). It is without effect on RORβ, RORγ, farnesoid X receptor, or liver X receptor α. SR 3335 evokes RORα-dependent effects both in vitro and in vivo, altering gene expression as well as gluconeogenesis.

Definition

ChEBI: N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-2-thiophenesulfonamide is a sulfonamide.

Properties of SR3335

storage temp.	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility	insoluble in H2O; ≥87.4 mg/mL in EtOH; ≥88.8 mg/mL in DMSO
form	solid
color	White to off-white

Safety information for SR3335

Computed Descriptors for SR3335

New Products

Dibenzoyl-L-tartaric acid Anhydrous (Resolution Reagent) Cis-Tosylate Dibenzo[b,f][1,4]thiazepin-11(10H)-one 1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-One 1-(4-methoxyphenyl)-4-(4-Nitrophenyl)Piperazine (IT-1) BOC Piperazine 1-Benzhydrylazetane-3-carbonitrile 8-oxa-1,3-diazaspiro[4.5]decane-2,4-dione (±)-amino(2-fluorophenyl)acetic acid 2-(2-Chlorophenyl)glycine AMINO-(3-CHLORO-PHENYL)-ACETIC ACID 2'-Fluoroacetophenone METHANOL-D1(OD) TERTIARY BUTANOL-D9 N-ETHYL-D5-AMINE HYDROCHLORIDE BENZOIC ACID-D CHLOROFORM-D TOLUENE-D3 Trans,trans muconic acid HC Blue-16 4-Amino-2-chloro-6,7-dimethoxyquinazoline Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate 2,3-Dimethoxypyridine 1-(3-Chlorophenyl)piperazine hydrochloride

You may like

Sr3335 95% CAS 293753-05-6
293753-05-6
View Details
SR3335 CAS 293753-05-6
293753-05-6
View Details
Product Introduction
View Details
Product Inrtroduction
View Details
DGO24
View Details
DGO25
View Details
DGO29
View Details
DGO32
View Details

Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.