Sofosbuvir IMpurity B
- CAS NO.:1496552-51-2
- Empirical Formula: C22H29ClN3O9P
- Molecular Weight: 545.91
- Update Date: 2024-07-02 08:54:57
What is Sofosbuvir IMpurity B?
The Uses of Sofosbuvir IMpurity B
Chloro Sofosbuvir is an impurity of Sofosbuvir (P839640); a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled Sofosbuvir as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.
Properties of Sofosbuvir IMpurity B
| Density | 1.43±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Soluble in DMSO |
| form | Solid |
| pka | 9.39±0.10(Predicted) |
| color | Light yellow to yellow |
Safety information for Sofosbuvir IMpurity B
Computed Descriptors for Sofosbuvir IMpurity B
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