SODIUM GLYCEROPHOSPHATE HYDRATE

Absorption

Peak serum phosphate concentration is reached in 4h .

Background

Sodium glycerophosphate is one of several glycerophosphate salts. It is used clinically to treat or prevent low phosphate levels . Glycerophosphate is hydrolyzed to inorganic phosphate and glycerol in the body . The extent of this reaction is dependent on the activity of serum alkaline phosphatases.

Indications

Sodium glycerophosphate is indicated for use as a source of phosphate in total parenteral nutrition . It is used in combination with amino acids, dextrose, lipid emulsions, and other electrolytes.

Pharmacokinetics

Glycerophosphate acts as a source of inorganic phosphate through hydrolysis .

Metabolism

Glycerophosphate is hydrolyzed to form inorganic phosphate . The extent of this reaction is dependent on serum alkaline phosphatase activity.