Sitagliptin Impurity 10
- CAS NO.：1253056-01-7
- Empirical Formula: C16H14F6N4O2
- Molecular Weight: 408.3
- MDL number: MFCD30747641
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-03-18 11:52:23
What is Sitagliptin Impurity 10?
The Uses of Sitagliptin Impurity 10
1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-hydroxy-4-(2,4,5-trifluorophenyl)-1-butanone is an intermediate in the synthesis of 3-Desamino-2,3-dehydro Sitagliptin (D281985), which is an impurity of Sitagliptin (S491000); a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes.
Properties of Sitagliptin Impurity 10
| Boiling point: | 542.2±60.0 °C(Predicted) |
| Density | 1.61±0.1 g/cm3(Predicted) |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | 13.69±0.20(Predicted) |
| form | Solid |
| color | White to Off-White |
Safety information for Sitagliptin Impurity 10
Computed Descriptors for Sitagliptin Impurity 10
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