SEA-0400
- CAS NO.：223104-29-8
- Empirical Formula: C21H19F2NO3
- Molecular Weight: 371.38
- MDL number: MFCD07772188
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-22 18:57:36
What is SEA-0400?
Description
SEA0400 is a selective inhibitor of the Na+/Ca2+ exchanger (IC50s = 5, 8.3, and 33 nM for inhibiting Na+-dependent Ca2+ uptake in rat astrocyte, microglia, and cortical neuron cell lines, respectively). It is reported to prevent dopaminergic neurotoxicity in an MPTP mouse model of Parkinson''s disease and to attenuate reperfusion injury in both in vitro and in vivo cerebral ischemic models.
The Uses of SEA-0400
SEA 0400 is a novel and selective inhibitor of Na+-Ca2+ exchanger.
Storage
Store at -20°C
Properties of SEA-0400
| Boiling point: | 485.0±45.0 °C(Predicted) |
| Density | 1.254±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | insoluble in H2O; ≥18.57 mg/mL in DMSO; ≥46.4 mg/mL in EtOH with ultrasonic |
| form | solid |
| pka | 4.04±0.10(Predicted) |
| color | White to khaki |
Safety information for SEA-0400
Computed Descriptors for SEA-0400
New Products
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