SCHIZOZYGINE

Empirical Formula: C20H20N2O3
Molecular Weight: 336.38
MDL number: MFCD07782311

What is SCHIZOZYGINE?

Description

The major alkaloid obtained from the bark and roots of Schizozygia caffaeoides (Boj.) Baill. The base has [α]²³_D + 15.5° (c 1.0, CHC1₃) and gives an ultraviolet spectrum having absorption maxima at 269 and 313 mil. The alkaloid possesses both antipyretic and broncholytic properties. When hydrogenated in AcOH in the presence of Pt0₂ it yields the dihydro derivative, m.p. 190-1°C;[α]²⁴_D + 29.4° (c 1.0, CHCI₃). Hydrogenation with LiAIH₄, however, gives deoxoschizozygine, m.p. 213-233°C (dec.); [α]²⁶_D + 82.9° (c 1.0, CHCI₃). The two reduction processes are protected by patents.

References

Renner, Kernweisz., Experientia, 19,244 (1963)
Structure:
Renner., Lloydia, 27,406 (1964)
Renner., Swiss Patent 451,182,15 May 1968
Renner., Swiss Patent 451,183,15 May 1968

Properties of SCHIZOZYGINE

Melting point:

192-4°C

Safety information for SCHIZOZYGINE

Computed Descriptors for SCHIZOZYGINE

New Products

Hendecanoic acid 2-Amino-5-cyanopyridine 2-Bromo-5-cyanopyridine DL-3-Amino-3-(2-methoxyphenyl)propionic acid 3-Hydroxypropionitrile 2-AMINO-3-METHYLQUINOLINE HYDROCHLORIDE 4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 4,4-Diethoxybutanenitrile 3′-Hydroxyacetophenone 5-fluoro-1,3-benzodioxole Tetracaine Hydrochloride Ep Grade 2,2,2-Trichloroethyl chloroformate 2-Bromo-6-fluoroaniline 2-Amino-4-phenyl-thiazole 4-Chloro-2-methyl quinoline 2-(Chloromethyl) quinazolin-4(3H)-one 5-Phenyl-[1,3,4]-thiadiazol-2-amine 2-Chloro-6-nitro benzothiazole 2-Aminobenzo[d]thiazol-4-ol 1-(4-Aminopiperidin-1-yl)-3,3,3-trifluoropropan-1-one 5-chloro-2-(4-methoxybenzyl)-4-(trifluoromethyl)pyridazin-3(2H)-one 3-cyanocyclohexane-1-carboxylic acid N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methacrylamide 2-(difluoromethyl)-4H-chromen-4-one