SB 224289 HYDROCHLORIDE
- CAS NO.：180084-26-8
- Empirical Formula: C32H32N4O3HCl
- Molecular Weight: 0
- MDL number: MFCD03788209
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-21 10:31:43
What is SB 224289 HYDROCHLORIDE?
The Uses of SB 224289 HYDROCHLORIDE
SB 224289A is a 5-HT1B antagonist.
The Uses of SB 224289 HYDROCHLORIDE
SB-224289 Hydrochloride is a selective SR-1B antagonist; 5-HT1B antagonist.
What are the applications of Application
SB-224289 hydrochloride is a selective SR-1B antagonist
Definition
ChEBI: SB 224289 hydrochloride is a hydrochloride that is the monohydrochloride salt of SB 224289. Selective 5-HT1B receptor antagonist (pKi = 8.2). Displays >60-fold selectivity over 5-HT1D, 5-HT1A, 5-HT1E, 5-HT1F, 5-HT2A and 5-HT2C receptors in radioligand binding and functional assays. Centrally active following oral administration in vivo. It has a role as a prodrug and a serotonergic antagonist. It contains a SB 224289(1+).
Storage
Room temperature
Properties of SB 224289 HYDROCHLORIDE
| storage temp. | Store at RT |
| solubility | Soluble to 10 mM in DMSO with gentle warming |
| form | Powder |
| color | White to off-white |
Safety information for SB 224289 HYDROCHLORIDE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P312:Call a POISON CENTER or doctor/physician if you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. |
Computed Descriptors for SB 224289 HYDROCHLORIDE
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