SAUCHINONE
Synonym(s):(5aα,7α,8β,8aβ,14aS*,14bβ)-5a,6,7,8,8a,14b-Hexahydro-7,8-dimethyl-5H-benzo[kl]bis[1,3]dioxolo[4,5-b:4′,5′-g]xanthen-5-one;(5aR,7R,8S,8aR,14aS,14bR)-5a,6,7,8,8a,14b-Hexahydro-7,8-dimethyl-5H-Benzo[kl]bis[1,3]dioxolo[4,5-b:4′,5′-g]xanthen-5-one
- CAS NO.：177931-17-8
- Empirical Formula: C20H20O6
- Molecular Weight: 356.37
- MDL number: MFCD08702698
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-22 18:57:36
What is SAUCHINONE?
The Uses of SAUCHINONE
Sauchinone is a lignan first isolated from the aerial parts of S. chinensis, a plant used in Asian medicine for its anti-inflammatory, anti-angiogenic, and anti-nociceptive activities. Sauchinone has numerous effects on isolated cells, including blocking NF-κB activation in LPS-stimulated macrophages, inducing heme oxygenase-1 transcription in endothelial cells, and attenuating oxidative-stress-induced damage in myoblasts. Sauchinone is extensively metabolized in vivo, but intraperitoneal administration significantly reduces myocardial infarct size induced by ischemia/reperfusion in mice.
What are the applications of Application
Sauchinone is a diastereomeric lignan with cytoprotective and anitoxidant activites
Properties of SAUCHINONE
| Melting point: | 224-226℃ |
| Boiling point: | 498.1±45.0 °C(Predicted) |
| Density | 1.43±0.1 g/cm3 (20 ºC 760 Torr) |
| storage temp. | 2-8°C |
| solubility | DMSO: soluble5mg/mL, clear (warmed) |
| form | powder |
| color | white to beige |
Safety information for SAUCHINONE
Computed Descriptors for SAUCHINONE
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