SAR131675
- CAS NO.：1092538-80-1
- Empirical Formula: C18H22N4O4
- Molecular Weight: 358.39
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-15 10:43:34
What is SAR131675?
The Uses of SAR131675
SAR131675 is a potent and selective VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine kinase activity and VEGFR-3 autophosphorylation in HEK cells. SAR131675 also dose dependently inhibited the prolife ration of primary human lymphatic cells, induced by the VEGFR-3 ligands VEGFC and VEGFD.
The Uses of SAR131675
SAR131675 is a potent and selective VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine kinase activity and VEGFR-3 autophosphorylation in HEK cells. SAR131675 also dose dependently inhibited the proliferation of primary human lymphatic cells, induced by the VEGFR-3 ligands VEGFC and VEGFD.
Properties of SAR131675
| Boiling point: | 592.2±50.0 °C(Predicted) |
| Density | 1.33±0.1 g/cm3(Predicted) |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| pka | 12.20±0.29(Predicted) |
| form | Solid |
| color | White to Pale Yellow |
Safety information for SAR131675
Computed Descriptors for SAR131675
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