safracin B
- CAS NO.：87578-99-2
- Empirical Formula: C28H36N4O7
- Molecular Weight: 540.61
- MDL number: MFCD01939882
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 02:56:47
What is safracin B?
Description
Safracin B (87578-99-2) is a novel antibiotic of the saframycin family produced by?Pseudomonas fluorescens.1?Safracin B displays antitumor activity against L1210 and P388 leukemias and B16 melanoma. Compared with safracin A, the toxic and effective doses were much lower. Safracin B also prolonged the life of tumor-bearing mice to a greater extent than safracin A.2
The Uses of safracin B
Safracin B is a new antibiotics from the family of Safracin produced by Pseudomonas fluorescens A2-2. Safracin B is an antibiotic that exhibits anti-tumor properties.
References
1) Ikeda?et al.?(1983),?Safracins, new antitumor antibiotics. I. Producing organism, fermentation and isolation; J. Antibiot. Tokyo,?36?1279 2) Okumoto?et al. (1985),?Activity of safracins A and B, heterocyclic quinone antibiotics, on experimental tumors in mice; J. Antibiot.Tokyo,?38?767
Properties of safracin B
| Boiling point: | 755.1±60.0 °C(Predicted) |
| Density | 1.41±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Soluble in DMSO (up to 20 mg/ml) |
| pka | 9.75±0.70(Predicted) |
| form | solid |
| color | Yellow-green |
| Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
Safety information for safracin B
Computed Descriptors for safracin B
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