safracin B
- CAS NO.：87578-99-2
- Empirical Formula: C28H36N4O7
- Molecular Weight: 540.61
- MDL number: MFCD01939882
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-08-06 15:14:14
What is safracin B?
Description
Safracin B (87578-99-2) is a novel antibiotic of the saframycin family produced by?Pseudomonas fluorescens.1?Safracin B displays antitumor activity against L1210 and P388 leukemias and B16 melanoma. Compared with safracin A, the toxic and effective doses were much lower. Safracin B also prolonged the life of tumor-bearing mice to a greater extent than safracin A.2
The Uses of safracin B
Safracin B is a new antibiotics from the family of Safracin produced by Pseudomonas fluorescens A2-2. Safracin B is an antibiotic that exhibits anti-tumor properties.
References
1) Ikeda?et al.?(1983),?Safracins, new antitumor antibiotics. I. Producing organism, fermentation and isolation; J. Antibiot. Tokyo,?36?1279 2) Okumoto?et al. (1985),?Activity of safracins A and B, heterocyclic quinone antibiotics, on experimental tumors in mice; J. Antibiot.Tokyo,?38?767
Properties of safracin B
| Boiling point: | 755.1±60.0 °C(Predicted) |
| Density | 1.41±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Soluble in DMSO (up to 20 mg/ml) |
| pka | 9.75±0.70(Predicted) |
| form | solid |
| color | Yellow-green |
| Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
Safety information for safracin B
Computed Descriptors for safracin B
New Products
2-Ethoxyphenol Methyl 2-methoxy-5-sulfamoylbenzoate 3,6-Dichloropyridazine Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate 3,6-Dichloro-4-Isopropylpyridazine 2-[(2-Ethoxyphenoxy)methyl]oxirane 4-Morpholinoaniline 2-Chloromethyl-6-methyl-pyridine 1-Indanone tert-Butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate 2-Pyridinecarboxaldehdye 6-Methyl-2-pyridinemethanol 4-Bromo-2-fluoro-N-methylbenzamide 3-Azetidinecarboxylic acid N-(2-(4-((4-Fluorobenzyl)carbamoyl)-5-hydroxy-6-methoxypyrimidin-2-yl)propan-2-yl)-5-methyl-1,3,4-oxadiazole-2-carboxamide (R)-4-Boc-morpholine-3-carboxylic acid (Required high chiral purity NLT:99.5%) Tetrahydro-3-(2-methyl-2- nitropropyl)-2H-pyran-2-one 3-Bromo-2-fluorobenzonitrile Desoximetasone Boron Triiodide Nicotinic acid RAPAMYCIN Pentachlorobenzonitrile BudesonideRelated products of tetrahydrofuran
![2-METHOXY-3-METHYL-[1,4]BENZOQUINONE](https://img.chemicalbook.in/CAS/GIF/2207-57-0.gif)
![[2-AMINO-1-(4-METHOXYPHENYL)ETHYL]DIMETHYLAMINE](https://img.chemicalbook.in/CAS/GIF/851169-57-8.gif)
You may like
-
1589503?95?6 2-((2,6-Difluorobenzyl)(ethoxycarbonyl)amino)-4-((dimethylamino)methyl)-5-(4-nitrophenyl)thiophene-3-carboxylic acid 99%View Details
1589503?95?6 -
2-Chlorophenyl diphenyl chloromethane 99%View Details
42074-68-0 -
6-(chloromethyl)pteridine-2,4-diamine monohydrochloride 82778?08?3 99%View Details
82778?08?3 -
Ethyl (Z)-3-(tetrahydro-2H-pyran-4-yl)acrylate 1373168-67-2 99%View Details
1373168-67-2 -
1,3-Dibromo-5-fluorobenzene 99%View Details
1435-51-2 -
729559-09-5 [N(E)]-N-Ethylidene-2-methyl-2-propanesulfinamide 99%View Details
729559-09-5 -
4-Isopropyl Thiophenol 4946-14-9 99%View Details
4946-14-9 -
2709271-25-8 99%View Details
2709271-25-8