Sacubitril Sodium
- CAS NO.：149690-05-1
- Empirical Formula: C24H28NNaO5
- Molecular Weight: 433.47259
- MDL number: MFCD32004488
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-31 10:02:37
What is Sacubitril Sodium ?
Description
Sacubitril Sodium is a potent orally active NEP (enkephalinase) inhibitor with an IC50 of 5 nM. Sacubitril Sodium enhances the tone of the natriuretic peptide (NP) system and exerts significant antihypertensive effects. Sacubitril Sodium is a component of the heart failure drug LCZ696. Sacubitril Sodium is used in heart failure, hypertension and COVID-19 studies.
The Uses of Sacubitril Sodium
Sacubitril Sodium Salt is a salt of Sacubitril, an antihypertensive drug used in combination with valsartan. The combination drug, valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name, Entresto, is a treatment for heart failure.
Properties of Sacubitril Sodium
| Melting point: | 163-165°C |
| storage temp. | -20°C, Hygroscopic |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| color | White to Off-White |
| Stability: | Hygroscopic |
Safety information for Sacubitril Sodium
Computed Descriptors for Sacubitril Sodium
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