(S)-(-)-Methyl 2-chloropropionate
- CAS NO.：73246-45-4
- Empirical Formula: C4H7ClO2
- Molecular Weight: 122.55
- MDL number: MFCD00062941
- EINECS: 412-470-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:18:41
What is (S)-(-)-Methyl 2-chloropropionate?
The Uses of (S)-(-)-Methyl 2-chloropropionate
(-)-Methyl α-Chloropropionate is used in the preparation of TIPTP which is a therapeutic agent for rheumatoid arthritis.
The Uses of (S)-(-)-Methyl 2-chloropropionate
Chiral starting material.
Properties of (S)-(-)-Methyl 2-chloropropionate
| Boiling point: | 80-82 °C110 mm Hg(lit.) |
| Density | 1.143 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | 101 °F |
| storage temp. | -20°C |
| form | clear liquid |
| color | Colorless to Almost colorless |
| optical activity | [α]20/D 26°, neat |
| BRN | 1720589 |
| CAS DataBase Reference | 73246-45-4(CAS DataBase Reference) |
| NIST Chemistry Reference | Propanoic acid, 2-chloro-, methyl ester, (s)-(73246-45-4) |
| EPA Substance Registry System | Propanoic acid, 2-chloro-, methyl ester, (2S)- (73246-45-4) |
Safety information for (S)-(-)-Methyl 2-chloropropionate
| Signal word | Warning |
| Pictogram(s) |
 Flame Flammables GHS02  Exclamation Mark Irritant GHS07  Health Hazard GHS08 |
| GHS Hazard Statements |
H226:Flammable liquids H302:Acute toxicity,oral H319:Serious eye damage/eye irritation H373:Specific target organ toxicity, repeated exposure |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P403+P235:Store in a well-ventilated place. Keep cool. P501:Dispose of contents/container to..… |
Computed Descriptors for (S)-(-)-Methyl 2-chloropropionate
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