(S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic acid methyl ester
- CAS NO.：177036-78-1
- Empirical Formula: C17H18O4
- Molecular Weight: 286.32
- MDL number: MFCD11865341
- EINECS: 1533716-785-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is (S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic acid methyl ester?
The Uses of (S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic acid methyl ester
(S)-α-Hydroxy-β-methoxy-β-phenyl-benzenepropanoic Acid Methyl Ester is an impurity in the synthesis of Ambrisentan (A575860), a nonpeptide endothelin ETA receptor antagonist. Antihypertensive. (Ambrisentan Hydroxyester Impurity)
Properties of (S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic acid methyl ester
| Melting point: | 61-62o C |
| Boiling point: | 440.7±40.0 °C(Predicted) |
| Density | 1.176 |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly, Sonicated), DMSO (Slightly) |
| form | Solid |
| pka | 12.37±0.20(Predicted) |
| color | White to Off-White |
| Stability: | Hygroscopic |
Safety information for (S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic acid methyl ester
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for (S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic acid methyl ester
New Products
6-Methyl-2-(p-tolyl)imidazo[1,2-a]pyridine 4-FLUOROBENZOYLACETONITRILE (S)-Glycidyl Phthalimide Maleic hydrazide 8-Bromo-3-methyl xanthine 5-Chlorothiophene-2-carboxylic acid 4'-Hydroxyacetophenone 3-Bromophenylacetic acid Tridecanoic acid Pentadecanoic acid 3-AMINO-3-(2-FLUORO-PHENYL)-PROPIONIC ACID Hendecanoic acid 2,3-Dihydro-5,6-dimethoxy-2-(4-piperidinylmethyl)-1H-inden-1-one hydrochloride 4-pyridine methanol Ethyl 3,3- diethoxypropionate 5-Bromo-pyridine-2-carbaldehyde 1-Bromo-3-phenylpropane 4-(4-Methylpiperazino)aniline 2-Deoxy-2,2-difluoro-D-erythro-pentofuranose-3,5-dibenzoate-1-methanesulfonate N-((S)-1-(3-(3-amino-4-chloro-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl)-6-(3-methyl-3-(methylsulfonyl)but-1-yn-1-yl)pyridin-2-yl)-2-(3,5-difluorophenyl)ethyl)-2-((3bS,4aR)-5,5-difluoro-3-(trifluoromethyl)-3b,4,4a,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)acetamide Methyl 2-(1-methyl-1H-pyrrol-2-yl)acetate 4-bromo-2-ethyl-3-fluorobenzoic acid 6-(chloromethyl)pteridine-2,4-diamine monohydrochloride 2-Chlorophenyl diphenyl chloromethaneRelated products of tetrahydrofuran
![2-[(4,6-Dimethyl-2-pyrimidinyl)oxy]-3,3-diphenyl-2-propenoic Acid](https://img.chemicalbook.in/CAS/20180529/GIF/1312092-82-2.gif)
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