(S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic acid methyl ester
- CAS NO.：177036-78-1
- Empirical Formula: C17H18O4
- Molecular Weight: 286.32
- MDL number: MFCD11865341
- EINECS: 1533716-785-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 02:25:38
What is (S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic acid methyl ester?
The Uses of (S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic acid methyl ester
(S)-α-Hydroxy-β-methoxy-β-phenyl-benzenepropanoic Acid Methyl Ester is an impurity in the synthesis of Ambrisentan (A575860), a nonpeptide endothelin ETA receptor antagonist. Antihypertensive. (Ambrisentan Hydroxyester Impurity)
Properties of (S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic acid methyl ester
| Melting point: | 61-62o C |
| Boiling point: | 440.7±40.0 °C(Predicted) |
| Density | 1.176 |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly, Sonicated), DMSO (Slightly) |
| form | Solid |
| pka | 12.37±0.20(Predicted) |
| color | White to Off-White |
| Stability: | Hygroscopic |
Safety information for (S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic acid methyl ester
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for (S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic acid methyl ester
New Products
2-Bromo-4-hydroxypyridine 2-Benzyl-1,1,3,3-tetramethylisoindoline AMINO-O-TOLYL-ACETIC ACID AMINO(2-BROMOPHENYL)ACETIC ACID 6-BROMOTETRAZOLO[1,5-A]PYRIDINE 1,3-Diazaspiro[4.5]decane-2,4-dione, 8,8-difluoro- 3-Oxocyclobutanecarboxylic acid AMINO-(3-FLUORO-PHENYL)-ACETIC ACID 4 pentyn 1 ol N-Vinylformamide Pyrrolo[1,2-a]pyrimidine-6-carboxylic acid, 4,6,7,8-tetrahydro-4-oxo-, sodium salt (1:1), (6S) Obidoxime hydrochloride API Piperazine, 1-(3-methoxyphenyl)-, hydrochloride (1:1) Decanoic acid, 2-[4-(phenylmethoxy)phenyl]ethyl ester 1-(2, 4-dichlorophenyl)-N-(2, 4-difluorophenyl)-N isopropyl-5-oxo-1H-1, 2, 4-trizole-4(5H)-carboxamide 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 Methyl trans-4-Aminocyclohexanecarboxylate Hydrochloride 3-(2-chloropyrimidin-4-yl)-1-methyl-1H-indole Tetrahydrofurfuryl Chloride tert-butyl 3-hydroxypyrrolidine-1-carboxylateRelated products of tetrahydrofuran
![2-[(4,6-Dimethyl-2-pyrimidinyl)oxy]-3,3-diphenyl-2-propenoic Acid](https://img.chemicalbook.in/CAS/20180529/GIF/1312092-82-2.gif)
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