(S)-2'-Amino-1,1'-binaphthalen-2-ol

Synonym(s):(S)-(−)-2-Amino-2′-hydroxy-1,1′-binaphthalene;(S)-NOBIN

CAS NO.：137848-29-4
Empirical Formula: C20H15NO
Molecular Weight: 285.34
MDL number: MFCD01882346
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 04:55:09

(S)-2'-Amino-1,1'-binaphthalen-2-ol Structural

What is (S)-2'-Amino-1,1'-binaphthalen-2-ol?

Chemical properties

Red crystal

The Uses of (S)-2'-Amino-1,1'-binaphthalen-2-ol

(S)-(-)-2′-Amino-1,1′-binaphthalen-2-ol or (S)-NOBIN, is a non-symmetrically substituted 1,1′-binaphthalene ligand. It can be used as a catalyst in the asymmetric synthesis of unnatural α-alkyl amino acids by phase-transfer catalysis (PTC). (S)-NOBIN can also be employed as starting material to prepare N-monoalkyl and N,N-dialkyl (S)-NOBIN analogs by reacting with aldehydes via reductive amination reaction. N-monoaryl derivatives are obtained from NOBIN via Hartwig?Buchwald arylation reaction.

Properties of (S)-2'-Amino-1,1'-binaphthalen-2-ol

Melting point:	171.0 to 175.0 °C
Boiling point:	471.5±30.0 °C(Predicted)
Density	1.275
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
pka	8.90±0.50(Predicted)
form	powder to crystal
color	White to Light red to Green
CAS DataBase Reference	137848-29-4(CAS DataBase Reference)

Safety information for (S)-2'-Amino-1,1'-binaphthalen-2-ol

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Environment GHS09
GHS Hazard Statements	H318:Serious eye damage/eye irritation H410:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P501:Dispose of contents/container to..…