(S)-2'-Amino-1,1'-binaphthalen-2-ol
Synonym(s):(S)-(−)-2-Amino-2′-hydroxy-1,1′-binaphthalene;(S)-NOBIN
- CAS NO.：137848-29-4
- Empirical Formula: C20H15NO
- Molecular Weight: 285.34
- MDL number: MFCD01882346
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:20:09
What is (S)-2'-Amino-1,1'-binaphthalen-2-ol?
Chemical properties
Red crystal
The Uses of (S)-2'-Amino-1,1'-binaphthalen-2-ol
(S)-(-)-2′-Amino-1,1′-binaphthalen-2-ol or (S)-NOBIN, is a non-symmetrically substituted 1,1′-binaphthalene ligand. It can be used as a catalyst in the asymmetric synthesis of unnatural α-alkyl amino acids by phase-transfer catalysis (PTC). (S)-NOBIN can also be employed as starting material to prepare N-monoalkyl and N,N-dialkyl (S)-NOBIN analogs by reacting with aldehydes via reductive amination reaction. N-monoaryl derivatives are obtained from NOBIN via Hartwig?Buchwald arylation reaction.
Properties of (S)-2'-Amino-1,1'-binaphthalen-2-ol
| Melting point: | 171.0 to 175.0 °C |
| Boiling point: | 471.5±30.0 °C(Predicted) |
| Density | 1.275 |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| pka | 8.90±0.50(Predicted) |
| form | powder to crystal |
| color | White to Light red to Green |
| CAS DataBase Reference | 137848-29-4(CAS DataBase Reference) |
Safety information for (S)-2'-Amino-1,1'-binaphthalen-2-ol
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Environment GHS09 |
| GHS Hazard Statements |
H318:Serious eye damage/eye irritation H410:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P501:Dispose of contents/container to..… |
Computed Descriptors for (S)-2'-Amino-1,1'-binaphthalen-2-ol
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