(S)-(+)-1,2,3,4-Tetrahydro-1-naphthol

Synonym(s):(S)-(+)-α-Tetralol

CAS NO.：53732-47-1
Empirical Formula: C10H12O
Molecular Weight: 148.2
MDL number: MFCD00063006
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 05:14:58

(S)-(+)-1,2,3,4-Tetrahydro-1-naphthol Structural

What is (S)-(+)-1,2,3,4-Tetrahydro-1-naphthol?

The Uses of (S)-(+)-1,2,3,4-Tetrahydro-1-naphthol

(S)?-?(+)?-?1,?2,?3,?4-?Tetrahydro-?1-?naphthol is a building block used in pharmaceutical chemistry such as in the synthesis of a potent and orally bioavailable GPR40 agonist acting as a novel insulin secretagogues with low risk of hypoglycemia

What are the applications of Application

(S)-(+)-1,2,3,4-Tetrahydro-1-naphthol is a chiral building block

General Description

Chiral building block.

Properties of (S)-(+)-1,2,3,4-Tetrahydro-1-naphthol

Melting point:	37-39 °C
Boiling point:	92 °C / 1.8mmHg
Density	1.09 g/mL at 25 °C(lit.)
refractive index	33 ° (C=2.5, CHCl3)
Flash point:	113 °C
solubility	almost transparency in Methanol
form	powder to crystal
pka	14.33±0.20(Predicted)
color	White to Almost white
optical activity	[α]20/D +33±1°, c = 2.5% in chloroform
BRN	2208779
CAS DataBase Reference	53732-47-1(CAS DataBase Reference)

Safety information for (S)-(+)-1,2,3,4-Tetrahydro-1-naphthol

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.