Ro 67-4853

CAS NO.：302841-89-0
Empirical Formula: C19H19NO4
Molecular Weight: 325.36
MDL number: MFCD20270618
SAFETY DATA SHEET (SDS)
Update Date: 2026-04-21 17:10:26

What is Ro 67-4853?

The Uses of Ro 67-4853

Ro 67-4853 is a positive allosteric modulator of metabotropic glutamate 1 receptor (1,2). Ro 67-4853 exhibits activity at all group I receptors such as human and rat mGlu1/mGlu5. It also enhance glutamate-induced calcium signaling through both the human and mouse mGlu1a receptors.

What are the applications of Application

Ro 67-4853 is an allosteric group I mGluR activator

Storage

Store at RT

Properties of Ro 67-4853

Melting point:	190-194°C
storage temp.	Refrigerator
solubility	Chloroform, Methanol
form	Solid
color	White

Safety information for Ro 67-4853

Signal word	Danger
Pictogram(s)	Exclamation Mark Irritant GHS07 Health Hazard GHS08 Environment GHS09
GHS Hazard Statements	H302:Acute toxicity,oral H361:Reproductive toxicity H372:Specific target organ toxicity, repeated exposure H410:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P201:Obtain special instructions before use. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P312:Call a POISON CENTER or doctor/physician if you feel unwell. P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

Computed Descriptors for Ro 67-4853

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